Title screen

[Ref.: 3 tit.]

Technetium-99m recovery process in the presence of stannous Sn (II) with the aim to determine it is necessary and sufficient quantity, that would provide a complete "recovery" of 99mTc in the reaction mixture has been investigated. The studies were identified conditions for receiving radioactive nanopreparations based on a modified molecule DTPA. The authors has been shown that the direct interaction of 99mTc eluate solution with a solution of a mixture of SnCl2 DTPAmod and radiochemical impurity content unreduced 99mTc (VII) in the preparation labeled with nanocolloids is 2,7% and the yield nanocolloids with the size of 100 nm is about 80%. The medical-biological testing of the agents 99mTc (IV) - DTPAmod on test animals for the determination of the functional suitability for the scintigraphic imaging of lymph nodes has been carried out.