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To study the diagnostic capabilities of emission single photon computed tomography with {199}Tl in imaging of breast cancer 90 women with breast diseases were included in the study. During the research high indications of specificity 96.7% were obtained in the detection of breast cancer. The sensitivity of breast cancer visualization was 95%, while in the detection of tumors smaller than 10mm, the sensitivity was 75%, in detecting tumors more than 10mm - 98%. Considering the high sensitivity and specificity of SPECT with 199Tl, we can recommend the use of this method as an additional diagnostic criterion in cases where other methods of radiation diagnosis and the results of morphological studies do not provide a clear answer.