The Importance of X-ray Crystal Structure Determinations for Pharmacy = Vyznam stanoveni rtg krystalovych struktur pro farmacii / B. Kratokhvil, E. I. Korotkova, M. P. Husak, A. M. Jegorov

Уровень набора: Chemicke ListyАльтернативный автор-лицо: Kratokhvil, B., chemist, Professor, doctor of chemical Sciences, 1949-, Bokhumil;Korotkova, E. I., chemist, Professor of Tomsk Polytechnic University, Doctor of chemical science, 1965-, Elena Ivanovna;Husak, M. P., Michal P.;Jegorov, A. M., Alexandr M.Коллективный автор (вторичный): Национальный исследовательский Томский политехнический университет (ТПУ), Институт природных ресурсов (ИПР), Кафедра физической и аналитической химии (ФАХ)Язык: .Резюме или реферат: X-ray structure analysis results have been widely used in the pharmaceutical research, development and control, especially for mapping polymorphism, to determine the chirality of active substances, in the pharmaceutical documentation and patent policy for many years. The greatest progress in X-ray diffraction techniques has been made in improving the quality of the poor material for successful data collection (magnetically oriented microcrystal arrays, serial snapshot crystallography). Prospects of the pharmaceutical application of X-ray crystallography lie in the acceleration of data collection, time-resolved structural studies obtained from the material of pharmaceutical batches without modification, and, in addition to that, in solving structures of semi-solid and amorphous phases and monitoring structural changes in drug formulations..Примечания о наличии в документе библиографии/указателя: [References: 38 tit.].Тематика: электронный ресурс | труды учёных ТПУ | рентгеновский анализ | структурный анализ | фармакология Ресурсы он-лайн:Щелкните здесь для доступа в онлайн
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[References: 38 tit.]

X-ray structure analysis results have been widely used in the pharmaceutical research, development and control, especially for mapping polymorphism, to determine the chirality of active substances, in the pharmaceutical documentation and patent policy for many years. The greatest progress in X-ray diffraction techniques has been made in improving the quality of the poor material for successful data collection (magnetically oriented microcrystal arrays, serial snapshot crystallography). Prospects of the pharmaceutical application of X-ray crystallography lie in the acceleration of data collection, time-resolved structural studies obtained from the material of pharmaceutical batches without modification, and, in addition to that, in solving structures of semi-solid and amorphous phases and monitoring structural changes in drug formulations.

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