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[References: 48 tit.]

Natural convection heat transfer combined with entropy generation in a square cavity filled with a nanofluid under the effect of variable temperature distribution along left vertical wall has been studied numerically. Governing equations formulated in dimensionless non-primitive variables with corresponding boundary conditions taking into account the Brownian diffusion and thermophoresis effects have been solved by finite difference method. Distribution of streamlines, isotherms, local entropy generation as well as Nusselt number has been obtained for different values of key parameters. It has been found that a growth of the amplitude of the temperature distribution along the left wall and an increase of the wave number lead to an increase in the average entropy generation. While an increase in abovementioned parameters for low Rayleigh number illustrates a decrease in average Bejan number.