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[References: p. 112-113 (16 tit.)]

One of the most strategic resources of a country is its science and technology complex. To be productive, scientists need excellent conditions for doing research. Consequently, they choose such place where they can work efficiently, they even leave their motherland for researching under better conditions. The study describes the key indicators of efficient research activity. To characterize the science of a country, we distinguish two groups: indicators of scientific and technological capabilities and indicators for assessing the impact of scientific productivity. We use statistical data of reports published in Russia from 2003 to 2014. We did the comparative analysis of performance indicators of research activity in some European and Asian OECD member countries. That provides an overview of the main trends of development and the state of world science. Using data analysis presented in Science Watch, Web of Science and Scopus databases, OECD STAN database, ANBERD, the data published by National Science Foundation and the RAND Corporation, we identify key indicators of research activity in the world. We point out the negative tendency of emigration of Russian scientists and highlight the main reasons of this process. In conclusion, we outline the main reasons of the crisis in Russian science.