Subject Index: p. 439-453.

Isotope Dilution Mass Spectrometry (IDMS) has become an essential tool in research laboratories and is increasingly used in routine analysis labs (including environmental, food safety and clinical applications). This is the first textbook to present a comprehensive and instructive view of the theory and applications of this growing technique. The first part of this textbook offers a uniform theoretical background, based both on the authors' experience in organic, speciation and elemental analysis and on the current published literature. In the second part, the comprehensive approach to the many applications of IDMS will ensure this text becomes an essential reference for any analytical laboratory. Emerging fields such as quantitative proteomics and metabolic studies are also discussed. Postgraduate students and laboratory staff will find this textbook to be a highly accessible guide to isotope dilution mass spectrometry providing the reader with a sound basis to working with this technique. Experienced researchers will benefit from designing experiments with IDMS methodologies in mind. The authors enjoy a strong reputation in the field of analytical chemistry and the reader will be familiar with their previous research.