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[References: 2 tit.]

A mathematical method of optimization of naphtha catalytic reforming and isomerization of industrial unit A100 ofPavlodar oil refinery combined with separation unit B300S was proposed. In order to achieve the required quality of theproducts of the splitter column for the C6 hydrocarbon content in the heavy gasoline fraction and the C7+ hydrocarboncontent in the light gasoline fraction, the research was carried out to optimize the process parameters. The obtained datawere checked for adequacy and confirmed by the simulation results presented for different modes of operation ofisomerization reactors and columns. The data can be used to solve real technological problems arising in production.