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[References: р. 96 (5 tit.)]

The paper shows the importance of innovation with regard to the economic well-being. The paper reflects the definition of the innovation resistance and the role of inertia in the innovation process. The innovation process is considered not only in terms of technical or technological changes, but also from the position of institutional transformations. The types and levels of innovation resistance are specified on the basis of the earlier studied literature. In addition, endogenous and exogenous factors of innovative resistance from the perspective of organization are determined. A general complex of approaches to overcoming the resistance to innovation changes is considered. The paper represents reasoning about the role of economic culture in the context of institutional changes. Finally, the author gives the arguments in favor of the fact that overcoming resistance to innovation changes for conducting economic transformations and improvement in the economic well-being is a must.