Effect of Na+,K+,2Cl- Cotransport Inhibitor Bumetanide on Electrical and Contractile Activity of Smooth Muscle Cells in Guinea Pig Ureter / I. V. Kovalev [et al.]
Уровень набора: Bulletin of Experimental Biology and Medicine, Scientific JournalЯзык: английский.Резюме или реферат: The effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 µM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 µM histamine, 10 µM mesatone, 5 mM tetraethylammonium, and 100 µM sodium nitroprusside. Our findings suggest that test substances modulate Na+,K+,2Cl- cotransport in smooth muscle cells..Примечания о наличии в документе библиографии/указателя: [References: p. 149 (15 tit.)].Аудитория: .Тематика: электронный ресурс | труды учёных ТПУ | bumetanide | biologically active substances | smooth muscle cells Ресурсы он-лайн:Щелкните здесь для доступа в онлайнНет реальных экземпляров для этой записи
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[References: p. 149 (15 tit.)]
The effect of Na+,K+,2Cl- cotransport inhibitor bumetanide on action potentials and contractions of smooth muscle cells in the ureter of guinea pigs evoked by electrical stimulation was studied by the method of double sucrose bridge. Bumetanide (10-100 µM) dose-dependently suppressed action potential and contractions of smooth muscle cells induced by 1-10 µM histamine, 10 µM mesatone, 5 mM tetraethylammonium, and 100 µM sodium nitroprusside. Our findings suggest that test substances modulate Na+,K+,2Cl- cotransport in smooth muscle cells.
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