Possibility of Using {99m}Tc-Labeled Macro-Aggregates of Serum Albumin and Diethylene Triamine Pentaacetic Acid in the Assessment Lung Ventilation and Perfusion in Patients with Chronic Obstructive Pulmonary Disease and Coronary Artery Disease / N. G. Krivonogov [et al.]
Уровень набора: (RuTPU)RU\TPU\network\4598, Advanced Materials Research : Radiation and nuclear techniques in material science, Scientific JournalЯзык: английский.Серия: Radiation Technologies in MedicineРезюме или реферат: Basic scintigraphy data reflecting into lung microcirculation and ventilation were studied at 12 patients with chronic obstructive pulmonary disease (COPD) of I-II degree against the background of coronary artery disease (CAD). The bilateral increase in an apical-basal gradient of perfusion that signaled about redistribution of a pulmonary blood-groove in the top parts of lungs and development of pulmonary hypertension and also slowing-down of alveolar-capillary permeability (ACP) was revealed. The revealed violations indicate more expressed changes of pulmonary microcirculation and ventilation at patients with COPD in combination with CAD and promote timely pharmacotherapy correction of the specified combined disease. Pulmonary ventilation/perfusion scintigraphy with {99m}Tc-labeled macro-aggregates of serum albumin (MAA) and diethylene triamine pentaacetic acid (DTPA) acid have all necessary properties for receiving high-quality lung scan..Аудитория: .Тематика: электронный ресурс | труды учёных ТПУ | болезни | ишемическая болезнь | легкие Ресурсы он-лайн:Щелкните здесь для доступа в онлайнTitle screen
Basic scintigraphy data reflecting into lung microcirculation and ventilation were studied at 12 patients with chronic obstructive pulmonary disease (COPD) of I-II degree against the background of coronary artery disease (CAD). The bilateral increase in an apical-basal gradient of perfusion that signaled about redistribution of a pulmonary blood-groove in the top parts of lungs and development of pulmonary hypertension and also slowing-down of alveolar-capillary permeability (ACP) was revealed. The revealed violations indicate more expressed changes of pulmonary microcirculation and ventilation at patients with COPD in combination with CAD and promote timely pharmacotherapy correction of the specified combined disease. Pulmonary ventilation/perfusion scintigraphy with {99m}Tc-labeled macro-aggregates of serum albumin (MAA) and diethylene triamine pentaacetic acid (DTPA) acid have all necessary properties for receiving high-quality lung scan.
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