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New experiments using atmospheric pressure plasma have found large application in biology and medicine. Cold air plasma treatment can be used to modify the surface of different materials for a variety of applications. The emission spectroscopy data confirmed the presence of different reactive species in the discharge gap. Surface treatments using this dry plasma technology offer an environmentally friendly alternative to the conventional wet chemical methods of microorganisms destruction, biological tissue treatment, in vitro and in vivo cell treatment. The use of cold plasma technology removes contaminants at the nanometer level.