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Precision methods and devices for the diagnostics of cardiovascular diseases are the one of the main directions of modern technology development in the field of medical instrument making. However, at this stage of development there are a few overall devices that allow for the diagnostics of cardiac muscle with precise accuracy and without internal interference in the body. This study considers the methods for measurement of biopotentials from the surface of the human body by means of electrocardiographic nanosensors. The device developed in the laboratory No. 63 of the Institute of Non-Destructive Testing of the National Research Tomsk Polytechnic University, its parameters and main characteristics are considered. The article focuses on the use of more sensitive equipment for more detailed study of the human body. The results of measurements carried out by means of the developed device are given.