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Analysis of geology and hydrogeology in the Yurubcheno-Tokhomo hydrocarbon kitchen showed that the Lower Cambrian Osa horizon is suitable for the disposal of large volumes of produced and wastewaters. Physicochemical numerical simulation of hydrochemistry using a 3D-model of filtration between injection (disposal) well and reservoir was used to estimate the contribution of the industrial effluent injection. It is established that the highest industrial change of the mineralogical composition and porosity-permeability of reservoir will be manifested during treated effluent disposal. A zone of industrial metasomatism, evolving in reservoir due to the wastewater injection, was calculated to be up to 800-840 m by the end of fifth year of landfill operation.