Synthesis and antiviral activity of antipyrine derivatives / A. N. Evstropov [et al.]
Уровень набора: Pharmaceutical Chemistry JournalЯзык: английский.Страна: .Резюме или реферат: In addition to antiinflammatory and analgesic activity, pyrazolones are known to possess antiviral activity [6-8]. Continuing this work, we have obtained some derivatives of antipyrine and 4- aminoantipyrine, and examined their antiviral spectrum of activity. In terms of their chemical structures, the compounds examined may be divided into the following groups: antipyrylamides of aliphatic aminoacids (I-XI), antipyryl- and isopropyl antipyrylamides of iodinated aromic carboxylic acids (XII-XX), 4-iodo- and 4-bromoantipyrine (XXI, XXII) and 4-formylantipyrine (XXIII), and derivatives of 4-formylantipyrine(XXIV, XXIX). ( 1 - Phenol-2,3-dimethyl-4-R- 5-pyrazolone)..Примечания о наличии в документе библиографии/указателя: [References: 15 tit.].Аудитория: .Тематика: электронный ресурс | труды учёных ТПУ | синтез | противовирусная активность | антипирин Ресурсы он-лайн:Щелкните здесь для доступа в онлайнTitle screen
[References: 15 tit.]
In addition to antiinflammatory and analgesic activity, pyrazolones are known to possess antiviral activity [6-8]. Continuing this work, we have obtained some derivatives of antipyrine and 4- aminoantipyrine, and examined their antiviral spectrum of activity. In terms of their chemical structures, the compounds examined may be divided into the following groups: antipyrylamides of aliphatic aminoacids (I-XI), antipyryl- and isopropyl antipyrylamides of iodinated aromic carboxylic acids (XII-XX), 4-iodo- and 4-bromoantipyrine (XXI, XXII) and 4-formylantipyrine (XXIII), and derivatives of 4-formylantipyrine(XXIV, XXIX). ( 1 - Phenol-2,3-dimethyl-4-R- 5-pyrazolone).
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