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[References: 23 tit.]

The purpose of the research: to study basic clinical and hormonal, metabolic, and psychological disturbances in children with obesity in various periods of the year. To evaluate the effectiveness of occupational therapy and identify the features of different systems of the body depending on the periods of the year based on calculation value of the integral indicator of health for children with obesity. In a survey of 298 children, of whom 200 people with obesity and 98 healthy children, month-to-month differences in the lipid and hormonal status of healthy children in the Siberian region were established, and clinical and laboratory characteristics of childhood obesity within a year were described. From December to July, in contrast to other months of the year, violations of psychoemotional status and decline in physical performance, improving lipid profile and proinflammatory cytokines were identified. Differentiated approach to the treatment of children with obesity, taking into account the monthly features of the main indicators of the clinical, hormonal, metabolic, and psychological status of these patients was substantiated.