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001 637293
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035 _a(RuTPU)RU\TPU\network\1393
090 _a637293
100 _a20140623a2011 k y0engy50 ba
101 0 _aeng
102 _aUS
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aStudy of DNA Interaction with Cobalt Ferrite Nanoparticles
_fA. G. Pershina [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 13 tit.]
330 _aInteraction of cobalt ferrite nanopowder and nucleic acid was investigated. Superparamagnetic cobalt ferrite nanoparticles (6–12 nm) were prepared by mechanochemical synthesis. Structure of the nanopowder was characterized using X-ray diffraction. It was shown that cobalt ferrite nanoparticles were associated with ssDNA and dsDNA in Tris-buffer resulting in bionanocomposite formation with mass weight relation nanoparticles: DNA 1:(0.083±0.003) and 1:(0.075±0.003) respectively. The mechanism of interaction between a DNA and cobalt ferrite nanoparticles was considered basing on the whole set of obtained data: FTIR-spectroscopy, analyzing desorption of DNA from the surface of the particles while changing the chemical content of the medium, and on the modeling interaction of specific biomolecule fragments with surface of a inorganic material. It was supposed that the linkage was based on coordination interaction of the phosphate groups and oxygen atoms heterocyclic bases of DNA with metal ions on the particle surface. These data can be used to design specific magnetic DNA-nanoparticles hybrid structures
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tJournal of Nanoscience and Nanotechnology
_d2001-
463 _tVol. 11, № 3
_v[P. 2673-2677]
_d2011
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _acobalt ferrite nanoparticles
610 1 _ainteraction
610 1 _ananobiocomposite
610 1 _anucleic acid
700 1 _aPershina
_bA. G.
_cbiologist
_cAssociate Professor of Tomsk Polytechnic University, Candidate of biological sciences
_f1981-
_gAleksandra Gennadievna
_2stltpush
_3(RuTPU)RU\TPU\pers\32466
701 1 _aSazonov
_bA. E.
701 1 _aNovikov
_bD. V.
701 1 _aKnyazev
_bA. S.
701 1 _aIzaak
_bT. I.
701 1 _aItin
_bV. I.
701 1 _aNaiden
_bE. P.
701 1 _aMagaeva
_bA. A.
701 1 _aTerechova
_bO. G.
801 2 _aRU
_b63413507
_c20151026
_gRCR
856 4 _uhttp://dx.doi.org/10.1166/jnn.2011.2739
942 _cCF