| 000 | 05035nla2a2200553 4500 | ||
|---|---|---|---|
| 001 | 641958 | ||
| 005 | 20231030040446.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\6889 | ||
| 035 | _aRU\TPU\network\6886 | ||
| 090 | _a641958 | ||
| 100 | _a20150609a2014 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aUS | ||
| 105 | _ay z 100zy | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aToxicity of the hybrid material based on low-dimensional structures of aluminum oxide _fO. V. Bakina [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: p. 34 (9 tit.)] | ||
| 330 | _aAluminum oxides of various morphology and phase composition, including pseudoboehmite, have wide application in medicine. The novel hybrid material from polymer fibers and low-dimensional structures of pseudoboehmite fixed on them can be used as a wound dressing due to its highly absorbent and adsorbent properties. The in vivo investigation of acute and chronic toxicity of the novel hybrid material after a single dermal application in the acute experiment for 8 and 24 hours with outbred male and female rats reveals no irritation or other pathological changes. The chronic toxicity testing of the material after multiple dermal applications at two doses causes no death of animals and no pathological changes in their general condition, weight dynamics, and visceral morphology. The macro- and microscopy of internal organs shows no pathological changes as compared to control animals. The results obtained bear witness to the low potential risk of toxicity when using the hybrid material as a wound dressing. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 |
_0(RuTPU)RU\TPU\network\4816 _tAIP Conference Proceedings |
|
| 463 | 0 |
_0(RuTPU)RU\TPU\network\4814 _tVol. 1623 : International Conference on Physical Mesomechanics of Multilevel Systems 2014, Tomsk, Russia, 3–5 September 2014 _o[proceedings] _fNational Research Tomsk Polytechnic University (TPU) _v[P. 31-34] _d2014 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aтоксичность | |
| 610 | 1 | _aгибридные материалы | |
| 610 | 1 | _aнаноразмерные структуры | |
| 610 | 1 | _aоксид алюминия | |
| 610 | 1 | _aфазовый состав | |
| 610 | 1 | _aпсевдобемит | |
| 610 | 1 | _aперевязочные материалы | |
| 610 | 1 | _aполимерные волокна | |
| 701 | 1 |
_aBakina _bO. V. _cspecialist in the field of medical technology _cresearcher of Tomsk Polytechnic University _f1979- _gOlga Vladimirovna _2stltpush _3(RuTPU)RU\TPU\pers\34696 |
|
| 701 | 1 |
_aGlazkova _bE. A. _cspecialist in the field of medical technology _csenior researcher of Tomsk Polytechnic University _f1963- _gElena Alekseevna _2stltpush _3(RuTPU)RU\TPU\pers\34699 |
|
| 701 | 1 |
_aSvarovskaya _bN. V. _cspecialist in the field of medical technology _csenior researcher of Tomsk Polytechnic University _f1965- _gNatalia Valentinovna _2stltpush _3(RuTPU)RU\TPU\pers\34703 |
|
| 701 | 1 |
_aLozhkomoev _bA. S. _cspecialist in the field of medical technology _cresearcher of Tomsk Polytechnic University _f1982- _gAleksandr Sergeevich _2stltpush _3(RuTPU)RU\TPU\pers\34706 |
|
| 701 | 1 |
_aDygay _bA. М. _gAleksandr |
|
| 701 | 1 |
_aChurin _bA. A. _gAleksey |
|
| 701 | 1 |
_aLerner _bM. I. _cspecialist in the field of mechanical engineering _cProfessor of Tomsk Polytechnic University, Doctor of technical sciences _f1956- _gMarat Izrailyevich _2stltpush _3(RuTPU)RU\TPU\pers\31423 |
|
| 701 | 1 |
_aPsakhie _bS. G. _cphysicist _chead of laboratory, Advisor to the rector, head of Department, Tomsk Polytechnic University, doctor of physico-mathematical Sciences _f1952- _gSergey Grigorievich _2stltpush _3(RuTPU)RU\TPU\pers\33038 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bКафедра физики высоких технологий в машиностроении (ФВТМ) _h2087 _2stltpush _3(RuTPU)RU\TPU\col\18687 |
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bКафедра физики высоких технологий в машиностроении (ФВТМ) _bСетевая научно-образовательная лаборатория "Динамическое моделирование и контроль ответственных конструкций" (НОЛ ММ) _h7379 _2stltpush _3(RuTPU)RU\TPU\col\20931 |
| 801 | 2 |
_aRU _b63413507 _c20170109 _gRCR |
|
| 856 | 4 | _uhttp://dx.doi.org/10.1063/1.4901475 | |
| 856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/35769 | |
| 942 | _cCF | ||