000 04012nlm1a2200505 4500
001 647477
005 20231030040803.0
035 _a(RuTPU)RU\TPU\network\12617
035 _aRU\TPU\network\12538
090 _a647477
100 _a20160412a2014 k y0engy50 ba
101 0 _aeng
102 _aNL
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aFabrication, ultra-structure characterization and in vitro studies of RF magnetron sputter deposited nano-hydroxyapatite thin films for biomedical applications
_fM. A. Surmeneva [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: p. 179-180 (59 tit.)]
330 _aA series of nanostructured low-crystalline hydroxyapatite (HA) coatings averaging 170, 250, and 440 nm in thickness were deposited onto previously etched titanium substrates through radio-frequency (RF) magnetron sputtering. The HA coatings were analyzed using infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning and transmission electron microscopy (SEM and TEM). Cross sections of the thin specimens were prepared by FIB to study the microstructure of the coatings by TEM. The deposition process formed nano-scale grains, generating an amorphous layer at the substrate/coating interface and inducing the growth of a columnar grain structure perpendicular to the substrate surface. A microstructural analysis of the film confirmed that the grain size and crystallinity increased when increasing the deposition time. The nanostructured HA coatings were not cytotoxic, as proven by in vitro assays using primary dental pulp stem cells and mouse fibroblast NCTC clone L929 cells. Low-crystallinity HA coatings with different thicknesses stimulated cells to attach, proliferate and form mineralized nodules on the surface better than uncoated titanium substrates.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tApplied Surface Science
_d1984-
463 _tVol. 317
_v[P. 172–180]
_d2014
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _abiomedical
610 1 _athin-films
610 1 _anano-hydroxyapatites
610 1 _aтонкие пленки
610 1 _aнано-гидроксиапатит
610 1 _aбиомедицина
701 1 _aSurmeneva (Ryabtseva)
_bM. A.
_cspecialist in the field of material science
_cengineer-researcher of Tomsk Polytechnic University, Associate Scientist
_f1984-
_gMaria Alexandrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\31894
701 1 _aSurmenev
_bR. A.
_cphysicist
_cAssociate Professor of Tomsk Polytechnic University, Senior researcher, Candidate of physical and mathematical sciences
_f1982-
_gRoman Anatolievich
_2stltpush
_3(RuTPU)RU\TPU\pers\31885
701 1 _aNikonova
_bY. A.
701 1 _aSelezneva
_bI. I.
701 1 _aIvanova
_bA. A.
_cphysicist
_cengineer-researcher of Tomsk Polytechnic University
_f1986-
_gAnna Aleksandrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\34747
701 1 _aPutlyaev
_bA. A.
701 1 _aPrymak
_bO.
701 1 _aEpple
_bM.
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bКафедра теоретической и экспериментальной физики (ТиЭФ)
_bЦентр технологий (ЦТ)
_h408
_2stltpush
_3(RuTPU)RU\TPU\col\20620
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bКафедра экспериментальной физики (ЭФ)
_h7596
_2stltpush
_3(RuTPU)RU\TPU\col\21255
801 2 _aRU
_b63413507
_c20161215
_gRCR
856 4 _uhttp://dx.doi.org/10.1016/j.apsusc.2014.08.104
942 _cCF