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| 001 | 648827 | ||
| 005 | 20231030040851.0 | ||
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| 090 | _a648827 | ||
| 100 | _a20160607a2016 k y0engy50 ba | ||
| 101 | 0 | _acze | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aThe Importance of X-ray Crystal Structure Determinations for Pharmacy _dVyznam stanoveni rtg krystalovych struktur pro farmacii _fB. Kratokhvil, E. I. Korotkova, M. P. Husak, A. M. Jegorov |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: 38 tit.] | ||
| 330 | _aX-ray structure analysis results have been widely used in the pharmaceutical research, development and control, especially for mapping polymorphism, to determine the chirality of active substances, in the pharmaceutical documentation and patent policy for many years. The greatest progress in X-ray diffraction techniques has been made in improving the quality of the poor material for successful data collection (magnetically oriented microcrystal arrays, serial snapshot crystallography). Prospects of the pharmaceutical application of X-ray crystallography lie in the acceleration of data collection, time-resolved structural studies obtained from the material of pharmaceutical batches without modification, and, in addition to that, in solving structures of semi-solid and amorphous phases and monitoring structural changes in drug formulations. | ||
| 461 | _tChemicke Listy | ||
| 463 |
_tVol. 110, iss. 1 _v[P. 40-47] _d2016 |
||
| 510 | 1 |
_aVyznam stanoveni rtg krystalovych struktur pro farmacii _zcze |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aрентгеновский анализ | |
| 610 | 1 | _aструктурный анализ | |
| 610 | 1 | _aфармакология | |
| 701 | 1 |
_aKratokhvil _bB. _cchemist _cProfessor, doctor of chemical Sciences _f1949- _gBokhumil _2stltpush _3(RuTPU)RU\TPU\pers\36881 |
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| 701 | 1 |
_aKorotkova _bE. I. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of chemical science _f1965- _gElena Ivanovna _2stltpush _3(RuTPU)RU\TPU\pers\31278 |
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| 701 | 1 |
_aHusak _bM. P. _gMichal P. |
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| 701 | 1 |
_aJegorov _bA. M. _gAlexandr M. |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут природных ресурсов (ИПР) _bКафедра физической и аналитической химии (ФАХ) _h94 _2stltpush _3(RuTPU)RU\TPU\col\18656 |
| 801 | 2 |
_aRU _b63413507 _c20200316 _gRCR |
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| 856 | 4 | _uhttp://www.chemicke-listy.cz/common/article-vol_110-issue_1-page_40.html | |
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