000 | 05153nla2a2200529 4500 | ||
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001 | 650261 | ||
005 | 20231030040939.0 | ||
035 | _a(RuTPU)RU\TPU\network\15473 | ||
035 | _aRU\TPU\network\15471 | ||
090 | _a650261 | ||
100 | _a20160928a2016 k y0engy50 ba | ||
101 | 0 | _aeng | |
102 | _aGB | ||
105 | _ay z 100zy | ||
135 | _adrcn ---uucaa | ||
181 | 0 | _ai | |
182 | 0 | _ab | |
200 | 1 |
_aRadiopharmaceuticals for SPECT Cancer Detection _fV. I. Chernov [et al.] |
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203 |
_aText _celectronic |
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300 | _aTitle screen | ||
320 | _a[References: 13 tit.] | ||
330 | _aThe purpose of the study was to assess the efficacy of single photon emission computed tomography (SPECT) with {199}Tl and {99m}Tc-MIBI in the detection of breast, laryngeal and hypopharyngeal cancers. Materials and Methods: a total of 220 patients were included into the study. Of them, there were 120 patients with breast lesions (100 patients with breast cancer and 20 patients with benign breast tumors) and 100 patients with laryngeal/hypopharyngeal diseases (80 patients with laryngeal/hypopharyngeal cancer and 20 patients with benign laryngeal/hypopharyngeal lesions). Results: no abnormal {199}Tl uptake was seen in all patients with benign breast and laryngeal lesions, indicating a 100% specificity of {199}Tl SPECT. In breast cancer patients, increased {199}Tl uptake in the breast was visualized in 94.8% patients, {99m}Tc-MIBI in 93.4% patients. Increased {199}Tl uptake in axillary lymph nodes was detected in 60% patients and {99m}Tc-MIBI in 93.1% patients. In patients with laryngeal/hypopharyngeal cancer, sensitivity of SPECT with {199}Tl and {99m}Tc-MIBI were 95%. The {199}Tl SPECT sensitivity in identification of regional lymph node metastases in patients with laryngeal/hypopharyngeal cancer was 75% and the{99m}Tc-MIBI SPECT sensitivity was 17%. Conclusion: the data obtained show that SPECT with {199}Tl and {99m}Tc-MIBI can be used as one of the additional imaging methods in detection of tumors. | ||
461 | 0 |
_0(RuTPU)RU\TPU\network\2008 _tIOP Conference Series: Materials Science and Engineering |
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463 | 0 |
_0(RuTPU)RU\TPU\network\15011 _tVol. 135 : Issues of Physics and Technology in Science, Industry and Medicine _oVIII International Scientific Conference, 1–3 June 2016, Tomsk, Russia _o[proceedings] _v[012008, 8 p.] _d2016 |
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610 | 1 | _aэлектронный ресурс | |
610 | 1 | _aтруды учёных ТПУ | |
610 | 1 | _aрадиофармпрепараты | |
610 | 1 | _aрадиофармацевтические препараты | |
610 | 1 | _aкомпьютерная томография | |
610 | 1 | _aопухоли | |
610 | 1 | _aрак | |
610 | 1 | _aоднофотонная компьютерная томография | |
610 | 1 | _aэмиссионная томография | |
701 | 1 |
_aChernov _bV. I. _cspecialist in the field of medical technology _clead engineer of Tomsk Polytechnic University, doctor of medical sciences _f1962- _gVladimir Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\34191 |
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701 | 1 |
_aMedvedeva _bА. А. _cspecialist in the field of medical technology _claboratory assistant of Tomsk Polytechnic University, candidate of medical science _f1975- _gAnna Aleksndrovna _2stltpush _3(RuTPU)RU\TPU\pers\37376 |
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701 | 1 |
_aZelchan _bR. V. _cspecialist in the field of medical technology _claboratory Tomsk Polytechnic University _f1984- _gRoman Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34194 |
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701 | 1 |
_aSinilkin _bI. G. _cspecialist in the field of medical technology _claboratory, Tomsk Polytechnic University, candidate of medical science _f1972- _gIvan Gennadjevich _2stltpush _3(RuTPU)RU\TPU\pers\34189 |
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701 | 1 |
_aStasyuk (Stasiuk) _bE. S. _cSpecialist in the field of nuclear power engineering _cResearcher of Tomsk Polytechnic University, Candidate of technical sciences _f1978- _gElena Sergeyevna _2stltpush _3(RuTPU)RU\TPU\pers\32656 |
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701 | 1 |
_aLarionova _bL. A. _cspecialist in the field of radiochemistry _cSenior researcher of Tomsk Polytechnic University _f1946- _gLyudmila Aleksandrovna _2stltpush _3(RuTPU)RU\TPU\pers\36172 |
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701 | 1 |
_aSlonimskaya _bE. M. |
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701 | 1 |
_aChoynzonov _bE. L. _cphysicist _cchief expert of Tomsk Polytechnic University _f1952- _gEvgeny Lkhamatsyrenovich _2stltpush _3(RuTPU)RU\TPU\pers\34575 |
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712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bФизико-технический институт (ФТИ) _bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР) _h6471 _2stltpush _3(RuTPU)RU\TPU\col\20054 |
712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bФизико-технический институт (ФТИ) _bКафедра прикладной физики (№ 12) (ПФ) _h46 _2stltpush _3(RuTPU)RU\TPU\col\18729 |
801 | 2 |
_aRU _b63413507 _c20170120 _gRCR |
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856 | 4 | _uhttp://dx.doi.org/10.1088/1757-899X/135/1/012008 | |
856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/34849 | |
942 | _cCF |