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035 _a(RuTPU)RU\TPU\network\15473
035 _aRU\TPU\network\15471
090 _a650261
100 _a20160928a2016 k y0engy50 ba
101 0 _aeng
102 _aGB
105 _ay z 100zy
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aRadiopharmaceuticals for SPECT Cancer Detection
_fV. I. Chernov [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 13 tit.]
330 _aThe purpose of the study was to assess the efficacy of single photon emission computed tomography (SPECT) with {199}Tl and {99m}Tc-MIBI in the detection of breast, laryngeal and hypopharyngeal cancers. Materials and Methods: a total of 220 patients were included into the study. Of them, there were 120 patients with breast lesions (100 patients with breast cancer and 20 patients with benign breast tumors) and 100 patients with laryngeal/hypopharyngeal diseases (80 patients with laryngeal/hypopharyngeal cancer and 20 patients with benign laryngeal/hypopharyngeal lesions). Results: no abnormal {199}Tl uptake was seen in all patients with benign breast and laryngeal lesions, indicating a 100% specificity of {199}Tl SPECT. In breast cancer patients, increased {199}Tl uptake in the breast was visualized in 94.8% patients, {99m}Tc-MIBI in 93.4% patients. Increased {199}Tl uptake in axillary lymph nodes was detected in 60% patients and {99m}Tc-MIBI in 93.1% patients. In patients with laryngeal/hypopharyngeal cancer, sensitivity of SPECT with {199}Tl and {99m}Tc-MIBI were 95%. The {199}Tl SPECT sensitivity in identification of regional lymph node metastases in patients with laryngeal/hypopharyngeal cancer was 75% and the{99m}Tc-MIBI SPECT sensitivity was 17%. Conclusion: the data obtained show that SPECT with {199}Tl and {99m}Tc-MIBI can be used as one of the additional imaging methods in detection of tumors.
461 0 _0(RuTPU)RU\TPU\network\2008
_tIOP Conference Series: Materials Science and Engineering
463 0 _0(RuTPU)RU\TPU\network\15011
_tVol. 135 : Issues of Physics and Technology in Science, Industry and Medicine
_oVIII International Scientific Conference, 1–3 June 2016, Tomsk, Russia
_o[proceedings]
_v[012008, 8 p.]
_d2016
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aрадиофармпрепараты
610 1 _aрадиофармацевтические препараты
610 1 _aкомпьютерная томография
610 1 _aопухоли
610 1 _aрак
610 1 _aоднофотонная компьютерная томография
610 1 _aэмиссионная томография
701 1 _aChernov
_bV. I.
_cspecialist in the field of medical technology
_clead engineer of Tomsk Polytechnic University, doctor of medical sciences
_f1962-
_gVladimir Ivanovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34191
701 1 _aMedvedeva
_bА. А.
_cspecialist in the field of medical technology
_claboratory assistant of Tomsk Polytechnic University, candidate of medical science
_f1975-
_gAnna Aleksndrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\37376
701 1 _aZelchan
_bR. V.
_cspecialist in the field of medical technology
_claboratory Tomsk Polytechnic University
_f1984-
_gRoman Vladimirovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34194
701 1 _aSinilkin
_bI. G.
_cspecialist in the field of medical technology
_claboratory, Tomsk Polytechnic University, candidate of medical science
_f1972-
_gIvan Gennadjevich
_2stltpush
_3(RuTPU)RU\TPU\pers\34189
701 1 _aStasyuk (Stasiuk)
_bE. S.
_cSpecialist in the field of nuclear power engineering
_cResearcher of Tomsk Polytechnic University, Candidate of technical sciences
_f1978-
_gElena Sergeyevna
_2stltpush
_3(RuTPU)RU\TPU\pers\32656
701 1 _aLarionova
_bL. A.
_cspecialist in the field of radiochemistry
_cSenior researcher of Tomsk Polytechnic University
_f1946-
_gLyudmila Aleksandrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\36172
701 1 _aSlonimskaya
_bE. M.
701 1 _aChoynzonov
_bE. L.
_cphysicist
_cchief expert of Tomsk Polytechnic University
_f1952-
_gEvgeny Lkhamatsyrenovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34575
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
_h6471
_2stltpush
_3(RuTPU)RU\TPU\col\20054
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bКафедра прикладной физики (№ 12) (ПФ)
_h46
_2stltpush
_3(RuTPU)RU\TPU\col\18729
801 2 _aRU
_b63413507
_c20170120
_gRCR
856 4 _uhttp://dx.doi.org/10.1088/1757-899X/135/1/012008
856 4 _uhttp://earchive.tpu.ru/handle/11683/34849
942 _cCF