| 000 | 03220nla2a2200349 4500 | ||
|---|---|---|---|
| 001 | 650281 | ||
| 005 | 20231030040940.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\15493 | ||
| 090 | _a650281 | ||
| 100 | _a20160929a2016 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 105 | _ay z 100zy | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aAntitumor activity of low-dimensional alumina structures _fM. S. Korovin, A. N. Fomenko |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: 54 tit.] | ||
| 330 | _aNano-dimensional materials have recently attracted much attention with respect to their potential role in medicine. Physical mechanisms of interaction of nanoparticles with tumor cells will help to develop new methods for cancer disease treatment. Based on aluminum oxide phases, positively charged low-dimensional structures have different shape: agglomerates of nanosheets, nameplates, cone-shaped nanoaggregates were synthesized with the help of aluminum nanoparticles. The cytotoxicity effect of these low-dimensional structures on A549, HeLa, MDA, PyMT tumor cells was studied. It was shown that agglomerates of nanosheets were more toxic for investigating cell lines. Agglomerates of nanosheets had a medium toxic effect at a concentration of 10?mg/ml while nameplates and cone-shaped nanoaggregates were nontoxic. The toxic effect of agglomerates of nanosheets correlates with their shape, mainly the presence of multiple edges. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 |
_0(RuTPU)RU\TPU\network\4816 _tAIP Conference Proceedings |
|
| 463 | 0 |
_0(RuTPU)RU\TPU\network\17033 _tVol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016 _oProceedings of the International conference, 22-25 March 2016, Tomsk, Russia _fNational Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas ; O. B. Naimark ; Yu. P. Sharkeev _v[020034, 9 p.] _d2016 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 700 | 1 |
_aKorovin _bM. S. _cspecialist in the field of medical technology _cresearcher of Tomsk Polytechnic University, candidate of biological sciences _f1980- _gMatvey Sergeevich _2stltpush _3(RuTPU)RU\TPU\pers\35814 |
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| 701 | 1 |
_aFomenko _bA. N. _cspecialist in the field of medical technology _cengineer at Tomsk Polytechnic University _f1985- _gAlla Nikolaevna _2stltpush _3(RuTPU)RU\TPU\pers\35011 |
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| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bКафедра физики высоких технологий в машиностроении (ФВТМ) _bСетевая научно-образовательная лаборатория "Медицинское материаловедение" (СНОЛ ММ) _h7443 _2stltpush _3(RuTPU)RU\TPU\col\21275 |
| 801 | 2 |
_aRU _b63413507 _c20170120 _gRCR |
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| 856 | 4 | _uhttp://dx.doi.org/10.1063/1.4960253 | |
| 856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/35781 | |
| 942 | _cCF | ||