| 000 | 02920nlm1a2200409 4500 | ||
|---|---|---|---|
| 001 | 651045 | ||
| 005 | 20231030041016.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\16294 | ||
| 090 | _a651045 | ||
| 100 | _a20161031a2016 k y0rusy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aMY | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aStudy of specific pharmacological activity of sodium salt (4-О-Β-Glucopyranosyloxy)-benzoic acid _fI. V. Smirnov [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: p. 24 (14 tit.)] | ||
| 330 | _aChronic inflammatory diseases of various genesis are prevalent today. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation, but their long-term use is associated with complications in the gastrointestinal tract, including peptic ulcers. We synthesized a molecule of sodium salt (4-О-B-glucopyranosyloxy)-benzoic acid. This substance has diuretic and anti-inflammatory activities. It should be noted that most of NSAIDs has analgesic effect. In this connection, the aim of this study was to evaluate the analgesic activity of sodium salt (4-О-B-glucopyranosyloxy)-benzoic acid. We studied analgesic effect in the test "acetic writhing". Sodium salt (4-О-B-glucopyranosyloxy)-benzoic acid significantly reduces the number of writhing by 14 units during the experiment, as an alternative criterion percent of animals with analgesia was 42.6%. Thus, in the test "acetic writhing" revealed the presence of the analgesic activity have developed drug average severity. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 |
_tJurnal Teknologi _d1977- |
||
| 463 |
_tVol. 78, iss. 6-8 _v[P. 21-24] _d2016 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aобезболивающие средства | |
| 610 | 1 | _aфенольные гликозиды | |
| 610 | 1 | _aнестероидные противовоспалительные препараты | |
| 701 | 1 |
_aSmirnov _bI. V. _gIvan Vladimirovich |
|
| 701 | 1 |
_aMurashko _bT. O. _gTatjyana Olegovna |
|
| 701 | 1 |
_aIvanov _bA. A. _cspecialist in the field of Electrophysics _cengineer of Tomsk Polytechnic University _f1990- _gAleksey Alekseevich _2stltpush _3(RuTPU)RU\TPU\pers\35679 |
|
| 701 | 1 |
_aBondarev _bA. A. _gAleksandr Aleksandrovich |
|
| 701 | 1 |
_aUdut _bV. V. _gVladimir Vasiljevich |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bЛаборатория № 1 _h6378 _2stltpush _3(RuTPU)RU\TPU\col\19035 |
| 801 | 2 |
_aRU _b63413507 _c20161031 _gRCR |
|
| 856 | 4 | _uhttp://dx.doi.org/10.11113/jt.v78.9047 | |
| 942 | _cCF | ||