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|---|---|---|---|
| 001 | 651633 | ||
| 005 | 20231030041043.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\16882 | ||
| 090 | _a651633 | ||
| 100 | _a20161117a2016 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aUS | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aMolecular and cellular bases of iron metabolism in humans _fI. V. Milto [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: p. 558-564 (200 tit.)] | ||
| 330 | _aIron is a microelement with the most completely studied biological functions. Its wide dissemination in nature and involvement in key metabolic pathways determine the great importance of this metal for uniand multicellular organisms. The biological role of iron is characterized by its indispensability in cell respiration and various biochemical processes providing normal functioning of cells and organs of the human body. Iron also plays an important role in the generation of free radicals, which under different conditions can be useful or damaging to biomolecules and cells. In the literature, there are many reviews devoted to iron metabolism and its regulation in proand eukaryotes. Significant progress has been achieved recently in understanding molecular bases of iron metabolism. The purpose of this review is to systematize available data on mechanisms of iron assimilation, distribution, and elimination from the human body, as well as on its biological importance and on the major iron-containing proteins. The review summarizes recent ideas about iron metabolism. Special attention is paid to mechanisms of iron absorption in the small intestine and to interrelationships of cellular and extracellular pools of this metal in the human body. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tBiochemistry (Moscow) | ||
| 463 |
_tVol. 81, iss. 6 _v[P. 549–564] _d2016 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aметаболизм | |
| 610 | 1 | _aмолекулярные основы | |
| 610 | 1 | _aклеточные основы | |
| 610 | 1 | _aорганизм человека | |
| 701 | 1 |
_aMilto _bI. V. _cchemist _csenior lecturer of Tomsk Polytechnic University, candidate of biological sciences _f1985- _gIvan Vasiljevich _2stltpush _3(RuTPU)RU\TPU\pers\37555 |
|
| 701 | 1 |
_aSukhodolo _bI. V. _gIrina Vladimirovna |
|
| 701 | 1 |
_aProkopjeva _bV. D. _gValentina Danilovna |
|
| 701 | 1 |
_aKlimentjeva _bT. K. _gTatjyana Konstantinovna |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bКафедра биотехнологии и органической химии (БИОХ) _h6810 _2stltpush _3(RuTPU)RU\TPU\col\18693 |
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_aRU _b63413507 _c20161117 _gRCR |
|
| 856 | 4 | _uhttp://dx.doi.org/10.1134/S0006297916060018 | |
| 942 | _cCF | ||