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001 651982
005 20231030041121.0
035 _a(RuTPU)RU\TPU\network\17245
035 _aRU\TPU\network\17242
090 _a651982
100 _a20161129a2016 k y0engy50 ba
101 0 _aeng
105 _ay z 100zy
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aRadiopharmaceuticals for SPECT Cancer Detection
_fV. I. Chernov [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 11 tit.]
330 _aThe purpose of the study was to assess the efficacy of single photon emission computed tomography (SPECT) with {199}Tl and {99}mTc-MIBI in the detection of breast, laryngeal and hypopharyngeal cancers. A total of 220 patients were included into the study: 120 patients with breast lesions (100 patients with breast cancer and 20 patients with benign breast tumors) and 100 patients with laryngeal/hypopharyngeal diseases (80 patients with laryngeal/hypopharyngeal cancer and 20 patients with benign laryngeal/hypopharyngeal lesions). No abnormal {199}Tl uptake was seen in all patients with benign breast and laryngeal lesions, indicating a 100% specificity of {199}Tl SPECT. In the breast cancer patients, the increased {199}Tl uptake in the breast was visualized in 94.8% patients, {99m}Tc-MIBI-in 93.4% patients. The increased {199}Tl uptake in axillary lymph nodes was detected in 60% patients, and {99m}Tc-MIBI-in 93.1% patients. In patients with laryngeal/hypopharyngeal cancer, the sensitivity of SPECT with {199}Tl and {99m}Tc-MIBI was 95%. The {199}Tl SPECT sensitivity in identification of regional lymph node metastases in the patients with laryngeal/hypopharyngeal cancer was 75% and the {99m}Tc-MIBI SPECT sensitivity was 17%. The data obtained showed that SPECT with {199}Tl and {99m}Tc-MIBI can be used as one of the additional imaging methods in detection of tumors.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 0 _0(RuTPU)RU\TPU\network\4816
_tAIP Conference Proceedings
463 0 _0(RuTPU)RU\TPU\network\17033
_tVol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016
_oProceedings of the International conference, 22-25 March 2016, Tomsk, Russia
_fNational Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas ; O. B. Naimark ; Yu. P. Sharkeev
_v[020011, 7 p.]
_d2016
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aрадиофармпрепараты
610 1 _aрак
610 1 _aэмиссионная томография
610 1 _aкомпьютерная томография
610 1 _aвизуализация
610 1 _aопухоли
610 1 _aядерная медицина
610 1 _aзлокачественные опухоли
701 1 _aChernov
_bV. I.
_cspecialist in the field of medical technology
_clead engineer of Tomsk Polytechnic University, doctor of medical sciences
_f1962-
_gVladimir Ivanovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34191
701 1 _aMedvedeva
_bА. А.
_cspecialist in the field of medical technology
_claboratory assistant of Tomsk Polytechnic University, candidate of medical science
_f1975-
_gAnna Aleksndrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\37376
701 1 _aZelchan
_bR. V.
_cspecialist in the field of medical technology
_claboratory Tomsk Polytechnic University
_f1984-
_gRoman Vladimirovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34194
701 1 _aSinilkin
_bI. G.
_cspecialist in the field of medical technology
_claboratory, Tomsk Polytechnic University, candidate of medical science
_f1972-
_gIvan Gennadjevich
_2stltpush
_3(RuTPU)RU\TPU\pers\34189
701 1 _aStasyuk (Stasiuk)
_bE. S.
_cSpecialist in the field of nuclear power engineering
_cResearcher of Tomsk Polytechnic University, Candidate of technical sciences
_f1978-
_gElena Sergeyevna
_2stltpush
_3(RuTPU)RU\TPU\pers\32656
701 1 _aLarionova
_bL. A.
_cspecialist in the field of radiochemistry
_cSenior researcher of Tomsk Polytechnic University
_f1946-
_gLyudmila Aleksandrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\36172
701 1 _aSlonimskaya
_bE. M.
701 1 _aChoynzonov
_bE. L.
_cphysicist
_cchief expert of Tomsk Polytechnic University
_f1952-
_gEvgeny Lkhamatsyrenovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34575
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
_h6471
_2stltpush
_3(RuTPU)RU\TPU\col\20054
801 2 _aRU
_b63413507
_c20170120
_gRCR
856 4 _uhttp://dx.doi.org/10.1063/1.4960230
856 4 _uhttp://earchive.tpu.ru/handle/11683/35771
942 _cCF