| 000 | 03864nla2a2200493 4500 | ||
|---|---|---|---|
| 001 | 652044 | ||
| 005 | 20231030041123.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\17307 | ||
| 035 | _aRU\TPU\network\17301 | ||
| 090 | _a652044 | ||
| 100 | _a20161130a2016 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 105 | _ay z 100zy | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aConcurrent thermochemoradiotherapy for brain high-grade glioma _fA. I. Ryabova [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 7 tit.] | ||
| 330 | _aDespite the achievements in the current strategies for treatment, the prognosis in malignant glioma patients remains unsatisfactory. Hyperthermia is currently considered to be the most effective and universal modifier of radiotherapy and chemotherapy. Preliminary treatment outcomes for 28 patients with newly diagnosed (23) and recurrent (5) high-grade gliomas were presented. All the patients received multimodality treatment including surgery, thermoche-moradiotherapy followed by 4 cycles of adjuvant chemotherapy. All the patients endured thermochemoradiotherapy well. A complication, limited skin burn (II stage), was diagnosed in two cases and treated conservatively without treatment interruption. A month after thermochemoradiotherapy the results were as follows: complete regression was achieved in 4 cases, partial regression in 4 cases, stable disease in 14 cases and disease progression in 6 cases (one of them is pseudo-progression). After completing the adjuvant chemotherapy 2 more patients demonstrated complete response and 1 patient had disease progression. Introduction of local hyperthermia in multimodal therapy of malignant glioma does not impair the combined modality treatment tolerability of patients with malignant gliomas. A small number of studied patients and short follow-up time do not allow making reliable conclusions about the impact of local hyperthermia on the treatment outcomes; however, there is a tendency towards the increase in disease-free survival in the patients with newly diagnosed malignant gliomas. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 |
_0(RuTPU)RU\TPU\network\4816 _tAIP Conference Proceedings |
|
| 463 | 0 |
_0(RuTPU)RU\TPU\network\17033 _tVol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016 _oProceedings of the International conference, 22-25 March 2016, Tomsk, Russia _fNational Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas ; O. B. Naimark ; Yu. P. Sharkeev _v[020058, 6 p.] _d2016 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aмозг | |
| 610 | 1 | _aзлокачественные опухоли | |
| 610 | 1 | _aзлокачественные новообразования | |
| 610 | 1 | _aглиомы | |
| 610 | 1 | _aгипертония | |
| 701 | 1 |
_aRyabova _bA. I. |
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| 701 | 1 |
_aNovikov _bV. A. |
|
| 701 | 1 |
_aChoinzonov _bЕ. L. |
|
| 701 | 1 |
_aGribova _bO. V. |
|
| 701 | 1 |
_aStartseva _bZh. А. |
|
| 701 | 1 |
_aBober _bE. E. |
|
| 701 | 1 |
_aFrolova _bI. G. |
|
| 701 | 1 |
_aBaranova _bA. V. _clinguist _cSenior Lecturer of Tomsk Polytechnic University _f1976- _gAnastasia Viktorovna _2stltpush _3(RuTPU)RU\TPU\pers\30948 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут природных ресурсов (ИПР) _bКафедра иностранных языков (ИЯПР) _h6735 _2stltpush _3(RuTPU)RU\TPU\col\18662 |
| 801 | 2 |
_aRU _b63413507 _c20170120 _gRCR |
|
| 856 | 4 | _uhttp://dx.doi.org/10.1063/1.4960277 | |
| 856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/35788 | |
| 942 | _cCF | ||