| 000 | 04950nla2a2200517 4500 | ||
|---|---|---|---|
| 001 | 652046 | ||
| 005 | 20231030041123.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\17309 | ||
| 035 | _aRU\TPU\network\17308 | ||
| 090 | _a652046 | ||
| 100 | _a20161130a2016 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 105 | _ay z 100zy | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aThe use of (99m}Tc-Al[2]O[3] for detection of sentinel lymph nodes in breast cancer _fI. G. Sinilkin [et al.] |
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| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 12 tit.] | ||
| 330 | _aPurpose: to study the feasibility of using the new radiopharmaceutical based on the technetium-99m-labeled gamma-alumina for identification of sentinel lymph nodes (SLNs) in breast cancer patients. The study included two groups of breast cancer patients who underwent single photon emission computed tomography (SPECT) and intraoperaive gamma probe identification of sentinel lymph nodes (SLNs). To identify SLNs, the day before surgery Group I patients (n=34) were injected with radioactive {99m}Tc-Al[2]O[3], and Group II patients (n=30) received 99mTc-labeled phytate colloid. A total of 37 SLNs were detected in Group I patients. The number of identified SLNs per patient ranged from 1 to 2 (the average number of identified SLNs was 1.08). Axillary lymph nodes were the most common site of SLN localization. 18 hours after {99m}Tc-Al[2]O[3] injection, the percentage of its accumulation in the SLN was 7-11% (of the counts in the injection site) by SPECT and 17-31% by gamma probe detection. In Group II SLNs were detected in 27 patients. 18 hours after injection of the phytate colloid the percentage of its accumulation in the SLN was 1.5-2% out of the counts in the injection site by SPECT and 4-7% by gamma probe. The new radiopharmaceutical based on the {99m}Tc-Al[2]O[3] demonstrates high accumulation in SLNs without redistribution through the entire lymphatic basin. The sensitivity and specificity of {99m}Tc-Al[2]O[3] were 100% for both SPECT and intraoperative gamma probe identification. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | 0 |
_0(RuTPU)RU\TPU\network\4816 _tAIP Conference Proceedings |
|
| 463 | 0 |
_0(RuTPU)RU\TPU\network\17033 _tVol. 1760 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications 2016 _oProceedings of the International conference, 22-25 March 2016, Tomsk, Russia _fNational Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas ; O. B. Naimark ; Yu. P. Sharkeev _v[020061, 4 p.] _d2016 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aлимфатические узлы | |
| 610 | 1 | _aрак | |
| 610 | 1 | _aрадиофармпрепараты | |
| 610 | 1 | _aэмиссионная томография | |
| 610 | 1 | _aкомпьютерная томография | |
| 610 | 1 | _aтехнеций-99м | |
| 610 | 1 | _aонкологические заболевания | |
| 701 | 1 |
_aSinilkin _bI. G. _cspecialist in the field of medical technology _claboratory, Tomsk Polytechnic University, candidate of medical science _f1972- _gIvan Gennadjevich _2stltpush _3(RuTPU)RU\TPU\pers\34189 |
|
| 701 | 1 |
_aChernov _bV. I. _cspecialist in the field of medical technology _clead engineer of Tomsk Polytechnic University, doctor of medical sciences _f1962- _gVladimir Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\34191 |
|
| 701 | 1 |
_aMedvedeva _bА. А. _cspecialist in the field of medical technology _claboratory assistant of Tomsk Polytechnic University, candidate of medical science _f1975- _gAnna Aleksndrovna _2stltpush _3(RuTPU)RU\TPU\pers\37376 |
|
| 701 | 1 |
_aZelchan _bR. V. _cspecialist in the field of medical technology _claboratory Tomsk Polytechnic University _f1984- _gRoman Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34194 |
|
| 701 | 1 |
_aSlonimskaya _bE. |
|
| 701 | 1 |
_aDoroshenko _bA. |
|
| 701 | 1 |
_aVarlamova _bN. V. _cbiochemist _cResearcher of Tomsk Polytechnic University, Candidate of biological sciences _f1975- _gNatalya Valeryevna _2stltpush _3(RuTPU)RU\TPU\pers\32659 |
|
| 701 | 1 |
_aSkuridin _bV. S. _cPhysicist, Specialist in the field of nuclear power engineering _cProfessor of Tomsk Polytechnic University, Doctor of technical sciences _f1946- _gViktor Sergeyevich _2stltpush _3(RuTPU)RU\TPU\pers\32655 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bФизико-технический институт (ФТИ) _bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР) _h6471 _2stltpush _3(RuTPU)RU\TPU\col\20054 |
| 801 | 2 |
_aRU _b63413507 _c20170120 _gRCR |
|
| 856 | 4 | _uhttp://dx.doi.org/10.1063/1.4960280 | |
| 856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/35790 | |
| 942 | _cCF | ||