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| 001 | 655891 | ||
| 005 | 20231030041404.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\22221 | ||
| 090 | _a655891 | ||
| 100 | _a20171011a2017 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aInfluence of Humic Acids Extracted from Peat by Different Methods on Functional Activity of Macrophages in Vitro _fE. S. Trofimova [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: p. 745 (14 tit.)] | ||
| 330 | _aWe studied activation of macrophages with humic acids extracted from peat of large deposits in the Tomsk region by two extraction methods: by hydroxide or sodium pyrophosphate. Humic acid of lowland peat types containing large amounts of aromatic carbon, phenolic and alcohol groups, carbohydrate residues and ethers, irrespectively of the extraction methods contained LPS admixture that probably determines their activating properties. Humic acid of upland peat types characterized by high content of carbonyl, carboxyl, and ester groups enhance NO production and reduce arginase expression, but these effects were minimized when sodium hydroxide was used as an extraction solvent. Pyrophosphate samples of the upland peat types were characterized by aromaticity and diversity of functional groups and have a significant advantage because of they induce specific endotoxin-independent stimulating action on antigen presenting cells. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tBulletin of Experimental Biology and Medicine | ||
| 463 |
_tVol. 162, iss. 6 _v[P. 741-745] _d2017 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aокиси | |
| 610 | 1 | _aазот | |
| 610 | 1 | _aмакрофации | |
| 610 | 1 | _aторф | |
| 610 | 1 | _aгуминовые кислоты | |
| 701 | 1 |
_aTrofimova _bE. S. _gEkaterina Sergeevna |
|
| 701 | 1 |
_aZykova _bM. V. _gMariya Vladimirovna |
|
| 701 | 1 |
_aLigacheva _bA. A. _gAnastasiya Aleksandrovna |
|
| 701 | 1 |
_aSherstoboev _bE. Yu. _gEvgeny Yurjevich |
|
| 701 | 1 |
_aZhdanov _bV. V. _gVadim Viktorovich |
|
| 701 | 1 |
_aBelousov _bM. V. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of Pharmaceutical Sciences _f1963- _gMikhail Valerievich _2stltpush _3(RuTPU)RU\TPU\pers\45418 |
|
| 701 | 1 |
_aYusubov _bM. S. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of chemical sciences _f1961- _gMekhman Suleiman-Ogly (Suleimanovich) _2stltpush _3(RuTPU)RU\TPU\pers\31833 |
|
| 701 | 1 |
_aKrivoshchekov _bS. V. _cchemist _cengineer of Tomsk Polytechnic University _f1987- _gSergey Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34574 |
|
| 701 | 1 |
_aDanilets _bM. G. _gMarina |
|
| 701 | 1 |
_aDygai _bA. V. _gAlexandr Mikhaylovich |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут природных ресурсов (ИПР) _bКафедра технологии органических веществ и полимерных материалов (ТОВПМ) _h6832 _2stltpush _3(RuTPU)RU\TPU\col\18659 |
| 801 | 2 |
_aRU _b63413507 _c20191129 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1007/s10517-017-3702-5 | |
| 942 | _cCF | ||