| 000 | 03754nlm1a2200505 4500 | ||
|---|---|---|---|
| 001 | 655916 | ||
| 005 | 20231030041405.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\22256 | ||
| 090 | _a655916 | ||
| 100 | _a20171012a2017 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aStudying the General Toxicity and Cumulative Properties of a Radiopharmaceutical Nanocolloid, 99mTc-Al2O3 _fN. V. Varlamova [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: p. 373 (8 tit.)] | ||
| 330 | _aWe studied toxicity of a new Russian radiopharmaceutical Nanocolloid, 99mTc-Al2O3. Tests for acute toxicity showed that this agent belongs to a class of moderate-toxicity substances and does not have cumulative properties. The evaluation of subchronic toxicity after subcutaneous injection of this product to rats (0.04, 0.2, and 0.4 ml/kg) and rabbits (0.02 and 0.2 ml/kg) for 7 days did not reveal changes in the general state, temperature, body weight, indices of the peripheral blood and bone marrow, functions of the heart, liver, kidneys, and nervous system, and morphological characteristics of the internal organs in animals. The drug does not produce a local irritant effect. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tBulletin of Experimental Biology and Medicine | ||
| 463 |
_tVol. 161, iss. 3 _v[P. 371-373] _d2016 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aрадиофармацевтика | |
| 610 | 1 | _aтоксичность | |
| 610 | 1 | _aсубхроническая токсичность | |
| 610 | 1 | _aдоклинические исследования | |
| 701 | 1 |
_aVarlamova _bN. V. _cbiochemist _cResearcher of Tomsk Polytechnic University, Candidate of biological sciences _f1975- _gNatalya Valeryevna _2stltpush _3(RuTPU)RU\TPU\pers\32659 |
|
| 701 | 1 |
_aChurin _bA. A. _gAleksey Aleksandrovich |
|
| 701 | 1 |
_aFomina _bT. I. _gTatjyana Ivanovna |
|
| 701 | 1 |
_aErmolaeva _bL. A. _gLyubov Aleksandrovna |
|
| 701 | 1 |
_aVetoshkina _bT. V. _gTatjyana Vladimirovna |
|
| 701 | 1 |
_aDubskaya _bT. Yu. _gTatjyana Yurjevna |
|
| 701 | 1 |
_aLamzina _bT. Yu. _gTatjyana Yurjevna |
|
| 701 | 1 |
_aFedorova _bE. P. _gElena Pavlovna |
|
| 701 | 1 |
_aNeupokoeva _bO. V. _gOksana Vladimirovna |
|
| 701 | 1 |
_aLarionova _bL. A. _cspecialist in the field of radiochemistry _cSenior researcher of Tomsk Polytechnic University _f1946- _gLyudmila Aleksandrovna _2stltpush _3(RuTPU)RU\TPU\pers\36172 |
|
| 701 | 1 |
_aSkuridin _bV. S. _cPhysicist, Specialist in the field of nuclear power engineering _cProfessor of Tomsk Polytechnic University, Doctor of technical sciences _f1946- _gViktor Sergeyevich _2stltpush _3(RuTPU)RU\TPU\pers\32655 |
|
| 701 | 1 |
_aNesterov _bE. A. _cPhysicist, Specialist in the field of nuclear power engineering _cResearcher of Tomsk Polytechnic University _f1976- _gEvgeny Alexandrovich _2stltpush _3(RuTPU)RU\TPU\pers\32657 |
|
| 701 | 1 |
_aChernov _bV. I. _cspecialist in the field of medical technology _clead engineer of Tomsk Polytechnic University, doctor of medical sciences _f1962- _gVladimir Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\34191 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bФизико-технический институт (ФТИ) _bЛаборатория радиационного контроля № 31 (Лаборатория РК № 31) _h6472 _2stltpush _3(RuTPU)RU\TPU\col\19161 |
| 801 | 2 |
_aRU _b63413507 _c20171012 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1007/s10517-016-3416-0 | |
| 942 | _cCF | ||