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035 _a(RuTPU)RU\TPU\network\22517
090 _a656114
100 _a20171025a2016 k y0rusy50 ba
101 0 _aeng
102 _aJP
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aAssessment of radiological techniques application possibility for non-invasive diagnostics of latent inflammatory processes in myocardium in patients with atrial fibrillation
_fS. I. Sazonova [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: p. 747-748 (54 tit.)]
330 _aObjective Aim was to study the performance of singlephoton emission computed tomography (SPECT) with 99mTc-pyrophosphate (99mTc-PYP) in diagnostics of chronic latent inflammation in myocardium of patients with atrial fibrillation (AF). Methods The research included 70 patients (the average age of 49.3 +- 10.2 years) with persistent form of idiopathic AF. All patients underwent myocardium SPECT with 99mTc-PYP and cardiac magnetic resonance imaging (CMR) before the ablation. During the ablation endomyocardium sampling for histological and immunohistochemical verification of myocarditis was performed. Results Sensitivity of SPECT with 99mTc-PYP in diagnoses of chronic latent myocarditis in patients with AF in relation to endomyocardial biopsy was 80 %, specificity- 83 % and diagnostic accuracy-82 %. Sensitivity, specificity and diagnostic accuracy of myocardium perfusion scintigraphy for diagnostics of latent myocarditis in relation to endomyocardial biopsy was 30, 50 and 50 % correspondingly. Also the close correlation between the size of the perfusion defect and the severity of myocardial fibrosis in patients with AF was revealed. Specificity of the Lake Louise criteria for diagnostics of latent myocarditis in relation to endomyocardial biopsy was 77.6 %, sensitivity-60 % and diagnostic accuracy-74.5 %. For only LGE specificity was 16 %, sensitivity-90 % and diagnostic accuracy-28 %. Conclusions The study showed the possibility of successful application of radionuclide methods for diagnoses of chronic latent myocarditis at AF. Taking into account high informative values the results of scintigraphy can be also considered as a promising additional criteria for selecting.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tAnnals of Nuclear Medicine
_d1987-
463 _tVol. 30, iss. 10
_v[P. 738–748]
_d2016
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aAtrial fibrillation
610 1 _aMyocarditis
610 1 _aCMR
610 1 _a99mTc-pyrophosphate
610 1 _aфибрилляция
610 1 _aмиокардит
610 1 _aрадиологические методы
610 1 _aнеинвазивная диагностика
610 1 _aпредсердия
610 1 _aвоспалительные процессы
701 1 _aSazonova
_bS. I.
_cspecialist in the field of medical technology
_cLaboratory assistant of Tomsk Polytechnic University, Candidate of medical Sciences
_f1974-
_gSvetlana Ivanovna
_2stltpush
_3(RuTPU)RU\TPU\pers\35320
701 1 _aIljyushenkova
_bYu. N.
_cspecialist in the field of medical technology
_cLaboratory assistant of Tomsk Polytechnic University
_f1985-
_gYuliya Nikolaevna
_2stltpush
_3(RuTPU)RU\TPU\pers\35322
701 1 _aLishmanov
_bYu. B.
_cspecialist in the field of medical technology
_clead engineer aof Tomsk Polytechnic University, doctor of medical sciences
_f1951-
_gYury Borisovich
_2stltpush
_3(RuTPU)RU\TPU\pers\34200
701 1 _aBatalov
_bR. E.
_gRoman Efimovich
701 1 _aSazonov
_bA. E.
_gAleksey Eduardovich
701 1 _aLarionova
_bL. A.
_cspecialist in the field of radiochemistry
_cSenior researcher of Tomsk Polytechnic University
_f1946-
_gLyudmila Aleksandrovna
_2stltpush
_3(RuTPU)RU\TPU\pers\36172
701 1 _aNesterov
_bE. A.
_cPhysicist, Specialist in the field of nuclear power engineering
_cResearcher of Tomsk Polytechnic University
_f1976-
_gEvgeny Alexandrovich
_2stltpush
_3(RuTPU)RU\TPU\pers\32657
701 1 _aVarlamova
_bN. V.
_cbiochemist
_cResearcher of Tomsk Polytechnic University, Candidate of biological sciences
_f1975-
_gNatalya Valeryevna
_2stltpush
_3(RuTPU)RU\TPU\pers\32659
701 1 _aRogovskaya
_bYu. V.
_gYuliya Viktorovna
701 1 _aShelkovnikova
_bT. V.
_gTatjyana Viktorovna
701 1 _aPopov
_bS. V.
_gSergey Valentinovich
712 0 2 _aНациональный исследовательский Томский политехнический университет (ТПУ)
_bФизико-технический институт (ФТИ)
_bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР)
_h6471
_2stltpush
_3(RuTPU)RU\TPU\col\20054
801 2 _aRU
_b63413507
_c20171025
_gRCR
856 4 _uhttps://doi.org/10.1007/s12149-016-1120-9
942 _cCF