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| 001 | 656752 | ||
| 005 | 20231030041443.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\23232 | ||
| 090 | _a656752 | ||
| 100 | _a20171211a2017 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aBG | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aAntioxidant activity and nontoxicity of extracts from Valeriana officinalis, Мelissa officinalis, Crataegus monogyna, Hypericum perforatum, Serratula coronatа and combinations Antistress 1 and Antistress 2 _fM. Katsarova [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: p. 97 (29 tit.)] | ||
| 330 | _aIn recent years, large number of preclinical and clinical studies support the hypothesis of a link between oxidativestress, anxiety and depression. In search of novel sources of antioxidants in the last years, medicinal plants traditionallyused in folk medicine have been extensively studied for their antioxidant activity (AOA). The purpose of this study wasto determine the antioxidant activity of the extracts of medicinal plants Valeriana officinalis, Мelissa officinalis,Crataegus monogyna, Hypericum perforatum, Serratula coronata and their combinations Antistress 1 and Antistress 2,which used as food supplements are recommended for chronic fatigue, anxiety and stress. This was done thoughmeasuring the Oxygen Radical Absorbance Capacity (ORAC), Hyrdoxyl Radical Averting Capacity (HORAC) and viaelectrochemical method (EM). The most pronounced is AOA of the extracts from M. officinalis(ORAC, 6751.0±214.3 µmol TE/g, HORAC, 1887.8±51.0 µmol GAE/g and EM, 24.901±1.445 ?mol/l.min) and H.perforatum (ORAC, 5950.5±328.4 µmol TE/g, HORAC, 2128.3±200.1 µmol GAE/g and EM, 23.605±1.334?mol/l.min), which could be a result of the high concentration of rosemary acid in the first extract and of flavonoids inthe second. They contribute to the greatest extent of the activity of Antistress 1 and Antistress 2. The conducted studyfor acute toxicity in vivo reported 100 percent survival of experimental animals, indicating that both individual andcombined extracts are non toxic to the tested animals. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tBulgarian Chemical Communications | ||
| 463 |
_tVol. 49, Special Issue G _v[P. 93-98] _d2017 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aэкстракты | |
| 610 | 1 | _aрастительное сырье | |
| 610 | 1 | _aтоксичность | |
| 610 | 1 | _aантиоксиданты | |
| 610 | 1 | _aвольтамперометрия | |
| 610 | 1 | _aтравы | |
| 701 | 1 |
_aKatsarova _bM. |
|
| 701 | 1 |
_aDimitrova _bS. Z. _gStela |
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| 701 | 1 |
_aLukanov _bL. K. _gLudmil |
|
| 701 | 1 |
_aSadakov _bF. _gFerit |
|
| 701 | 1 |
_aPlotnikov _bE. V. _cchemist _cEngineer of Tomsk Polytechnic University _f1983- _gEvgeny Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\32469 |
|
| 701 | 1 |
_aKandilarov _bI. |
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| 701 | 1 |
_aKostadinova _bI. |
|
| 701 | 1 |
_aDenev _bP. N. _gPetko Nedyalkov |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут природных ресурсов (ИПР) _bКафедра физической и аналитической химии (ФАХ) _h94 _2stltpush _3(RuTPU)RU\TPU\col\18656 |
| 801 | 2 |
_aRU _b63413507 _c20171211 _gRCR |
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| 856 | 4 | _uhttp://www.bcc.bas.bg/BCC_Volumes/Volume_49_Special_G_2017/BCC-49-G-Katsarova-93-98.pdf | |
| 942 | _cCF | ||