| 000 | 02946nlm1a2200433 4500 | ||
|---|---|---|---|
| 001 | 656926 | ||
| 005 | 20231030041449.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\23406 | ||
| 090 | _a656926 | ||
| 100 | _a20171221a2018 k y0engy50 ba | ||
| 101 | 1 | _aeng | |
| 102 | _aNL | ||
| 135 | _aarcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aSurfaces functionalized by graphene oxide nanosheets for single cell investigations _fL. Dedelaite [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: p. 1742-1743 (51 tit.)] | ||
| 330 | _aIn this research development of sensor suitable for single cell investigation is reported. To achieve this goal biocompatible graphene oxide (GO) nanosheets were applied as substrates for separated cell immobilization. GO nanosheets are particularly interesting due to their biocompatibility, scalability, and possibility to be deposited via simple surface functionalization protocols. In this context, we rise the hypothesis that GO nanosheets can be used to treat substrates for single cell studies. We investigated this hypothesis using several pristine and GO-modified highly oriented pyrolytic graphite, objective glass slides, polished silicon wafers, polydimethylsiloxane and mica substrates. A significantly larger frequency of single cell deposition events was observed on all substrates modified by GO. We exploited the GO functionalization to advance the Raman spectroscopy based analysis of the chemical composition of individual cells gathering different Raman spectra with respect to that collected from yeast cell colonies. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tSensors and Actuators B: Chemical | ||
| 463 |
_tVol. 255, pt. 2 _v[P. 1735-1743] _d2018 |
||
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aсубстраты | |
| 610 | 1 | _aспектроскопия | |
| 610 | 1 | _aраманскопы | |
| 610 | 1 | _aиммобилизация | |
| 701 | 1 |
_aDedelaite _bL. _gLina |
|
| 701 | 1 |
_aRodriguez (Rodriges) Contreras _bR. D. _cVenezuelan physicist, doctor of science _cProfessor of Tomsk Polytechnic University _f1982- _gRaul David _2stltpush _3(RuTPU)RU\TPU\pers\39942 |
|
| 701 | 1 |
_aAndriukonis _bE. _gEivydas |
|
| 701 | 1 |
_aHietschold _bM. _gMichael |
|
| 701 | 1 |
_aZahn _bD. R. T. _gDietrich |
|
| 701 | 1 |
_aRamanavicius _bA. _gArunas |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bИнститут физики высоких технологий (ИФВТ) _bКафедра лазерной и световой техники (ЛиСТ) _h65 _2stltpush _3(RuTPU)RU\TPU\col\18690 |
| 801 | 2 |
_aRU _b63413507 _c20220311 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1016/j.snb.2017.08.187 | |
| 942 | _cCF | ||