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001 657716
005 20231030041523.0
035 _a(RuTPU)RU\TPU\network\24429
035 _aRU\TPU\network\23687
090 _a657716
100 _a20180313a2017 k y0engy50 ba
101 0 _aeng
105 _ay z 100zy
135 _adrgn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aSynthesis and Characterization of Electro-Explosive Magnetic Nanoparticles for Biomedical Applications
_fO. V. Bakina [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 9 tit.]
330 _aNowadays there are new magnetic nanostructures based on bioactive metals with low toxicity and high efficiency for a wide range of biomedical applications including drugs delivery, antimicrobial drugs design, cells' separation and contrasting. For such applications it is necessary to develop highly magnetic particles with less than100 nm in size. In the present study magnetic nanoparticles Fe, Fe[3]O[4] and bimetallic Cu/Fe with the average size of 60- 90 nm have been synthesized by electrical explosion of wire in an oxygen or argon atmosphere. The produced nanoparticles have been characterized with transmission electron microscopy, X-ray phase analysis, and nitrogen thermal desorption. The synthesized particles have shown antibacterial activity to gram-positive (S. aureus, MRSA) and gramnegative (E. coli, P. aeruginosa) bacteria. According to the cytological data Fe, Fe[3]O[4]and Cu/Fe nanoparticles have effectively inhibited viability of cancer cell lines Neuro-2a and J774. The obtained nanoparticles are promising for new antimicrobial drugs and antitumor agents' development
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 0 _0(RuTPU)RU\TPU\network\4816
_tAIP Conference Proceedings
463 0 _0(RuTPU)RU\TPU\network\24427
_tVol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17)
_oProceedings of the International conference, 23–26 May 2017, Tomsk, Russia
_fNational Research Tomsk Polytechnic University (TPU) ; eds. E. Y. Gutmanas, O. B. Naimark, Yu. P. Sharkeev
_v[020004, 4 p.]
_d2017
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aсинтез
610 1 _aхарактеристики
610 1 _aмагнитные наночастицы
610 1 _aнаночастицы
610 1 _aбиомедицинское применение
610 1 _aтоксичность
610 1 _aпросвечивающая электронная микроскопия
610 1 _aэлектрический взрыв
610 1 _aрентгенофазовый анализ
610 1 _aтермическая десорбция
610 1 _aраковые заболевания
610 1 _aпротивоопухолевые препараты
610 1 _aпротивомикробные средства
701 1 _aBakina
_bO. V.
701 1 _aGlazkova
_bE. A.
701 1 _aSvarovskaya
_bN. V.
701 1 _aLerner
_bM. I.
_cspecialist in the field of mechanical engineering
_cProfessor of Tomsk Polytechnic University, Doctor of technical sciences
_f1956-
_gMarat Izrailyevich
_2stltpush
_3(RuTPU)RU\TPU\pers\31423
701 1 _aKorovin
_bM. S.
701 1 _aFomenko
_bA. N.
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИнженерная школа новых производственных технологий
_bОтделение материаловедения
_h7871
_2stltpush
_3(RuTPU)RU\TPU\col\23508
801 2 _aRU
_b63413507
_c20180321
_gRCR
856 4 _uhttps://doi.org/10.1063/1.5001583
856 4 _uhttp://earchive.tpu.ru/handle/11683/46879
942 _cCF