| 000 | 03456nlm1a2200409 4500 | ||
|---|---|---|---|
| 001 | 658830 | ||
| 005 | 20231030041608.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\26954 | ||
| 090 | _a658830 | ||
| 100 | _a20181129a2018 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aElectrochemical oxidability of antioxidants: Synergism and antagonism in mixes _fN. N. Sazhina [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 29 tit.] | ||
| 330 | _aTo investigate electrochemical oxidability of antioxidants to reveal synergistic and antagonistic effects in mixes. Materials and Methods: Electrochemical oxidability of some widely used antioxidants, including uric acid, glutathione, trolox, ascorbic acid, gallic acid, Mexidol, and potassium fenozan, was investigated by the amperometric approach. Results: All obtained electrochemical oxidability values correlate well with antioxidant activity parameters of the same compounds measured by other methods. The measurements of the electrochemical oxidability for binary mixes of substances were tested to reveal any synergistic actions. The experimental results and calculated values overlap for various combinations of tested mixes. It testifies to the absence of interaction between them (both synergism and antagonism) in the oxidation process. Conclusions: The constants of oxidation were defined for different antioxidants and mixes by amperometric approach. Most mixes of probed compounds revealed absence of interaction between them in oxidation process. In some cases (mainly with glutathione and ascorbic acid), antagonism takes place, deteriorating effects of their joint application. Apparently, a partial reduction of glutathione by ascorbic acid leads to excess of the measured value over calculated value. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tJournal of Pharmacy and Bioallied Sciences | ||
| 463 |
_tVol. 10, iss. 2 _v[P. 60-65] _d2018 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aамперометрия | |
| 610 | 1 | _aантагонизм | |
| 610 | 1 | _aантиоксиданты | |
| 610 | 1 | _aсинергизм | |
| 701 | 1 |
_aSazhina _bN. N. _gNataljya |
|
| 701 | 1 |
_aPlotnikov _bE. V. _cchemist _cEngineer of Tomsk Polytechnic University _f1983- _gEvgeny Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\32469 |
|
| 701 | 1 |
_aKorotkova _bE. I. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of chemical science _f1965- _gElena Ivanovna _2stltpush _3(RuTPU)RU\TPU\pers\31278 |
|
| 701 | 1 |
_aDorozhko _bE. V. _cchemist _cEngineer of Tomsk Polytechnic University _f1979- _gElena Vladimirovna _2stltpush _3(RuTPU)RU\TPU\pers\32174 |
|
| 701 | 1 |
_aVoronova _bO. A. _cchemist _cAssistant of Tomsk Polytechnic University, Candidate of chemical sciences _f1979- _gOlesya Aleksandrovna _2stltpush _3(RuTPU)RU\TPU\pers\32169 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИнженерная школа природных ресурсов _bОтделение химической инженерии _h8085 _2stltpush _3(RuTPU)RU\TPU\col\23513 |
| 801 | 2 |
_aRU _b63413507 _c20181129 _gRCR |
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| 856 | 4 | _uhttp://dx.doi.org/10.4103/JPBS.JPBS_203_17 | |
| 942 | _cCF | ||