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035 _a(RuTPU)RU\TPU\network\27916
090 _a659366
100 _a20190214a2019 k y0engy50 ba
101 0 _aeng
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aJanus glycosides of next generation: Synthesis of 4-(3-chloropropoxy)phenyl and 4-(3-azidopropoxy)phenyl glycosides
_fE. V. Stepanova [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 77 tit.]
330 _aEfficient procedures for the preparative synthesis of per-O-acyl derivatives of 4-(3-chloropropoxy)phenyl (CPP) glycosides of a series of common mono- and disaccharides (d-glucose, d-galactose, d-mannose, l-rhamnose, d-arabinofuranose, d-glucosamine, lactose) are described. The CPP glycosides obtained were transformed in almost quantitative yields to the corresponding unprotected 4-(3-azidopropoxy)phenyl (APP) glycosides, which could become next-generation Janus glycosides with cleavable spacer aglycon, ready for conjugation or further transformation.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tCarbohydrate Research
463 _tVol. 471
_v[P. 95-104]
_d2019
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aglycosylation
610 1 _aspacer aglycon
610 1 _ajanus aglycon
610 1 _acleavable aglycon
610 1 _aгликозилирование
610 1 _aагликоны
701 1 _aStepanova
_bE. V.
_cchemist
_cengineer of Tomsk Polytechnic University
_f1978-
_gElena Vladimirovna
_2stltpush
_3(RuTPU)RU\TPU\pers\34245
701 1 _aAbronina
_bP. I.
_gPolina Igorevna
701 1 _aZinin
_bA. I.
_gAleksandr Ivanovich
701 1 _aChizhov
_bA. O.
_gAleksandr Olegovich
701 1 _aKononov
_bL. O.
_gLeonid Olegovich
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИсследовательская школа химических и биомедицинских технологий (ИШХБМТ)
_c(2017- )
_h8120
_2stltpush
_3(RuTPU)RU\TPU\col\23537
801 2 _aRU
_b63413507
_c20190214
_gRCR
856 4 _uhttps://doi.org/10.1016/j.carres.2018.11.013
942 _cCF