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|---|---|---|---|
| 001 | 659571 | ||
| 005 | 20231030041633.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\28186 | ||
| 035 | _aRU\TPU\network\16202 | ||
| 090 | _a659571 | ||
| 100 | _a20190304a2018 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aCH | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aPhysicochemical Characterization and Antioxidant Activity of Humic Acids Isolated from Peat of Various Origins _fM. V. Zykova, I. A. Schepetkin, M. V. Belousov [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: 68 tit.] | ||
| 330 | _aAlthough humic acids (HAs) from peat exhibit various therapeutic properties, there is little information available concerning their physicochemical and antioxidant properties. To address this issue, nine different types of peat, including oligotrophic, mesotrophic, and minerotrophic peat samples, were used for isolation of HA fractions by basic (HAb) and pyrophosphate (HAp) extractions. Physical parameters of the HAs were analyzed by UV-Vis, fluorescent, infrared (IR), and electron paramagnetic resonance (EPR) spectroscopy. Average Mr of the fractions ranged from 17.2 to 39.7 kDa, while their humification index (HIX) varied from 0.49 to 1.21. HAp fractions had a higher content of aromatic structures compared to HAb fractions. Moreover, HAp fractions had a significantly higher content of phenolic OH groups (3.6 ± 0.5 mmol/g) versus HAb (3.1 ± 0.5 mmol/g). All HA fractions exhibited antioxidant activity in radical scavenging and electrochemical assays, and their EPR signal had a single line with g = 2.0035, which is consistent with semiquinone type radicals. Furthermore, the HIX was found to be important in determining the number of semiquinone-type free radicals in the HA structures. Overall, these data provide a molecular basis to explain at least part of the beneficial therapeutic properties of peat-derived HAs. | ||
| 461 | _tMolecules | ||
| 463 |
_tVol. 23, iss. 4 _v[753, 15 p.] _d2018 |
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| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _apeat | |
| 610 | 1 | _ahumic acid | |
| 610 | 1 | _aantioxidant | |
| 610 | 1 | _aethnopharmacology | |
| 610 | 1 | _asemiquinone | |
| 610 | 1 | _anatural products | |
| 610 | 1 | _aторф | |
| 610 | 1 | _aгуминовые кислоты | |
| 610 | 1 | _aантиоксиданты | |
| 610 | 1 | _aсемихиноны | |
| 701 | 1 |
_aZykova _bM. V. _gMaria |
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| 701 | 1 |
_aSchepetkin (Shchepyotkin) _bI. A. _cdoctor-biophysicist _cleading researcher of Tomsk Polytechnic University, candidate of medical science _f1962- _gIgor Aleksandrovich _2stltpush _3(RuTPU)RU\TPU\pers\37358 |
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| 701 | 1 |
_aBelousov _bM. V. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of Pharmaceutical Sciences _f1963- _gMikhail Valerievich _2stltpush _3(RuTPU)RU\TPU\pers\45418 |
|
| 701 | 1 |
_aKrivoshchekov _bS. V. _cchemist _cengineer of Tomsk Polytechnic University _f1987- _gSergey Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34574 |
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| 701 | 1 |
_aLogvinova _bL. A. _gLyudmila |
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| 701 | 1 |
_aBratishko _bK. A. _gKristina |
|
| 701 | 1 |
_aYusubov _bM. S. _cchemist _cProfessor of Tomsk Polytechnic University, Doctor of chemical sciences _f1961- _gMekhman Suleiman-Ogly (Suleimanovich) _2stltpush _3(RuTPU)RU\TPU\pers\31833 |
|
| 701 | 1 |
_aRomanenko _bS. V. _cspecialist in the field of ecology and life safety _chead of the Department of Tomsk Polytechnic University, doctor of chemical Sciences _f1972- _gSergey Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34932 |
|
| 701 | 1 |
_aQuinn _bM. T. _gMark |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий (ИШХБМТ) _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20201103 _gRCR |
|
| 856 | 4 | 0 | _uhttps://dx.doi.org/10.3390/molecules23040753 |
| 942 | _cCF | ||