| 000 | 03516nlm1a2200517 4500 | ||
|---|---|---|---|
| 001 | 660088 | ||
| 005 | 20231030041653.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\29035 | ||
| 090 | _a660088 | ||
| 100 | _a20190424a2018 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aDE | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aEfficient N-Heterocyclic Carbene/Ruthenium Catalytic Systems for the Alcohol Amidation with Amines: Involvement of Poly-Carbene Complexes? _fCheng Hua [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 22 tit.] | ||
| 330 | _aThe atom-economic direct amidation of alcohols with amines has been recently highlighted as an attractive and promising transformation. Among the versatile reported catalytic systems, in situ generated N-heterocyclic carbene (NHC)/ruthenium (Ru) catalytic systems have demonstrated their advantages such as easy operation and use of commercial Ru compounds. However, the existing catalyst loadings are relatively high, and additional insights for the in situ catalyst generation are still not well-documented. In this work, a variety of benzimidazole-based NHC precursors were initially synthesized. Through the screening of various NHC precursors and other reaction conditions, active in situ catalytic systems were discovered for the efficient amide synthesis. Notably, the catalyst loading is as low as 0.5 mol?%. Furthermore, additional experiments were performed to validate the rationale for the superiority of the current catalytic systems over our previous system. It was observed that the ligand structure is one of the reasons for the higher activity. In addition, the higher ratio of the NHC precursor/[Ru] is another important factor for the improvement. Further HR-MS analysis identified the formation of two mono-NHC-Ru species as major species and two Ru species bearing multiple NHC ligands as minor species. Hopefully, the efficient and readily-accessible catalytic systems reported herein could demonstrate great potential for further practical applications. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tChemCatChem | ||
| 463 |
_tVol. 10, iss. 19 _v[P. 4338-4345] _d2018 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aruthenium | |
| 610 | 1 | _aN-heterocyclic carbene (s) | |
| 610 | 1 | _aatom-economic | |
| 610 | 1 | _aamide synthesis | |
| 610 | 1 | _aрутений | |
| 610 | 1 | _aгетероциклический ряд | |
| 610 | 1 | _aкарбены | |
| 610 | 1 | _aсинтез | |
| 701 | 0 | _aCheng Hua | |
| 701 | 0 | _aXiong Mao-Qian | |
| 701 | 0 | _aZhang Ni | |
| 701 | 0 | _aWang Hua-Jing | |
| 701 | 0 | _aMiao Yang | |
| 701 | 0 | _aSu Wei | |
| 701 | 0 | _aYuan Ye | |
| 701 | 0 | _aChen Cheng | |
| 701 | 1 |
_aVerpoort _bF. V. K. _cChemical Engineer _cProfessor of Tomsk Polytechnic University, doctor of chemical Sciences _f1963- _gFrensis Valter Kornelius _2stltpush _3(RuTPU)RU\TPU\pers\35059 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий (ИШХБМТ) _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210312 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1002/cctc.201800945 | |
| 942 | _cCF | ||