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100 _a20190703a2018 k y0engy50 ba
101 0 _aeng
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aApplication of cold plasma for performing a typical resection of the spleen
_fA. N. Aleinik [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 26 tit.]
330 _aWhen the spleen is damaged, severe bleeding develops which can lead to death. The aim of this study was to evaluate the effectiveness of cold plasma treatment for performing partial splenectomy as a new organ-preserving technique. Adult male rabbits were used as experimental animals. They were randomly separated into control (5 in total) and experimental (30 in total) groups. Animals from the experimental group had partial splenectomy with subsequent coagulation by cold plasma. Blood loss, complete blood count (CBC), histological tissue samples and splenograms were investigated after 60 min, 3, 5, 14, 90, 180 days following plasma treatment. Contrast-enhanced MR—angiography with 'Gadovist' was performed on the 90th day. The structure of the organ was normalized in the late periods. MR-imaging of the microcirculatory bed on the 90th day after the operation was normal. The effective hemostasis of the spleen in the experiment occurred after treatment with the plasma for 90–100 s. After hemostasis with plasma, spleen parenchyma was damaged, manifested by the general adaptation syndrome but at a later time it regenerated with the formation of a connective tissue scar at a later time. Functions of the spleen were not damaged. These results demonstrate the high efficiency of cold plasma treatment during surgical interventions.
333 _aРежим доступа: по договору с организацией-держателем ресурса
461 _tBiomedical Physics and Engineering Express
463 _tVol. 4, iss. 5
_v[055026, 7 p.]
_d2018
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aлечение
610 1 _aхолодная плазма
610 1 _aселезенка
610 1 _aхирургические вмешательства
701 1 _aAleinik
_bA. N.
_cphysicist
_cSenior researcher of Tomsk Polytechnic University, Candidate of physical and mathematical science
_f1944-
_gAleksandr Nikonorovich
_2stltpush
_3(RuTPU)RU\TPU\pers\31074
701 1 _aBaykov
_bA. N.
_gAleksandr Nikolaevich
701 1 _aShevtsova
_bN.
701 1 _aSemichev
_bE. V.
_gEvgeny Vasiljevich
701 1 _aBushlanov
_bP. S.
_gPavel Sergeevich
701 1 _aTurgunova
_bN. D.
_gNataljya Dzhuraboevna
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИнженерная школа ядерных технологий
_bОтделение ядерно-топливного цикла
_h7864
_2stltpush
_3(RuTPU)RU\TPU\col\23554
801 2 _aRU
_b63413507
_c20190703
_gRCR
856 4 _uhttps://doi.org/10.1088/2057-1976/aadb2d
942 _cCF