| 000 | 03460nlm1a2200469 4500 | ||
|---|---|---|---|
| 001 | 662005 | ||
| 005 | 20231030041806.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\33138 | ||
| 035 | _aRU\TPU\network\31498 | ||
| 090 | _a662005 | ||
| 100 | _a20200424a2020 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_a99mTc-labeled monosaccharide kits: development methods and quality control _fE. S. Stasyuk (Stasiuk), V. S. Skuridin, A. S. Rogov [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 14 tit.] | ||
| 330 | _aThe paper presents the procedure for planning an experiment to create standard sets of reagents for a technetium-99m generator based on glucose derivatives. All stages are presented from researching the required quantities of a substance, a reducing agent, a stabilizer and auxiliary components to developing lyophilized kits and conducting quality control. The radiochemical purity of radiopharmaceuticals prepared on the basis of the developed kits ranged from 90.0 to 99.0%. We also showed the functional suitability of the developed preparations on C57B1/6j mice with an implanted malignant tumor - Lewis lung carcinoma. | ||
| 461 | _tScientific Reports | ||
| 463 |
_tVol. 10 _v[5121, 9 p.] _d2020 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _acancer imaging | |
| 610 | 1 | _adrug development | |
| 610 | 1 | _aвизуализация | |
| 610 | 1 | _aрак | |
| 610 | 1 | _aразработка | |
| 610 | 1 | _aлекарства | |
| 701 | 1 |
_aStasyuk (Stasiuk) _bE. S. _cSpecialist in the field of nuclear power engineering _cResearcher of Tomsk Polytechnic University, Candidate of technical sciences _f1978- _gElena Sergeyevna _2stltpush _3(RuTPU)RU\TPU\pers\32656 |
|
| 701 | 1 |
_aSkuridin _bV. S. _cPhysicist, Specialist in the field of nuclear power engineering _cProfessor of Tomsk Polytechnic University, Doctor of technical sciences _f1946- _gViktor Sergeyevich _2stltpush _3(RuTPU)RU\TPU\pers\32655 |
|
| 701 | 1 |
_aRogov _bA. S. _cRadiochemist _cEngineer of Tomsk Polytechnic University _f1986- _gAlexander Sergeyevich _2stltpush _3(RuTPU)RU\TPU\pers\32658 |
|
| 701 | 1 |
_aZelchan _bR. V. _cspecialist in the field of medical technology _claboratory Tomsk Polytechnic University _f1984- _gRoman Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\34194 |
|
| 701 | 1 |
_aSadkin _bV. L. _cPhysicist _cAssociate Scientist of Tomsk Polytechnic University, candidate of technical Sciences _f1986- _gVladimir Leonidovich _2stltpush _3(RuTPU)RU\TPU\pers\32654 |
|
| 701 | 1 |
_aVarlamova _bN. V. _cbiochemist _cResearcher of Tomsk Polytechnic University, Candidate of biological sciences _f1975- _gNatalya Valeryevna _2stltpush _3(RuTPU)RU\TPU\pers\32659 |
|
| 701 | 1 |
_aNesterov _bE. A. _cPhysicist, Specialist in the field of nuclear power engineering _cResearcher of Tomsk Polytechnic University _f1976- _gEvgeny Alexandrovich _2stltpush _3(RuTPU)RU\TPU\pers\32657 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bФизико-технический институт _bЛаборатория № 31 ядерного реактора _h6471 _2stltpush _3(RuTPU)RU\TPU\col\20054 |
| 801 | 2 |
_aRU _b63413507 _c20210514 _gRCR |
|
| 856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/65323 | |
| 856 | 4 | _uhttps://doi.org/10.1038/s41598-020-61707-7 | |
| 942 | _cCF | ||