| 000 | 03252nlm1a2200529 4500 | ||
|---|---|---|---|
| 001 | 663002 | ||
| 005 | 20231030041840.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\34170 | ||
| 035 | _aRU\TPU\network\28833 | ||
| 090 | _a663002 | ||
| 100 | _a20210119a2019 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aCellular and Molecular Basis of Osteoblastic and Vascular Niches in the Processes of Hematopoiesis and Bone Remodeling (A Short Review of Modern Views) _fK. A. Yurova, O. G. Khaziakhmatova, E. S. Melashchenko [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 330 | _aIn evolutionary processes, human bone marrow has formed as an organ depot of various types of cells that arise from hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). Vital HSC activity is controlled through molecular interactions with the niche microenvironment. The review describes current views on the formation of key molecular and cellular components of the HSC niche, which ensure maintenance of home ostasis in stem cell niches, obtained from studies of their role in regulating the proliferation and differentiation of HSCs, including the physiological, reparative and pathological remodeling of bone tissue. Due to rapid developments in biotechnology, tissue bioengineering, and regenerative medicine, information can be useful for developing biomimetic and bioinspired materials and implants that provide an effective bone/bone marrow recovery process after injuries and, to a greater extent, diseases of various etiologies. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tCurrent Pharmaceutical Design | ||
| 463 |
_tVol. 25, iss. 6 _v[P. 663-669] _d2019 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _aстволовые клетки | |
| 610 | 1 | _aбиоматериалы | |
| 610 | 1 | _aкости | |
| 610 | 1 | _aвнеклеточный матрикс | |
| 610 | 1 | _aкроветворно-лимфатическая система | |
| 610 | 1 | _aбиоинженерия | |
| 610 | 1 | _aextracellular matrix | |
| 610 | 1 | _abiomaterials | |
| 610 | 1 | _abone | |
| 610 | 1 | _atissue remodeling. | |
| 701 | 1 |
_aYurova _bK. A. |
|
| 701 | 1 |
_aKhaziakhmatova _bO. G. |
|
| 701 | 1 |
_aMelashchenko _bE. S. |
|
| 701 | 1 |
_aMelashchenko _bV. V. |
|
| 701 | 1 |
_aShunkin _bE. O. _gEgor |
|
| 701 | 1 |
_aShupletsova _bV. V. _gValeria |
|
| 701 | 1 |
_aIvanov _bP. A. _gPavel |
|
| 701 | 1 |
_aKhlusov _bI. A. _cbiophysicist _cProfessor of Tomsk Polytechnic University, doctor of medical Sciences _f1963- _gIgor Albertovich _2stltpush _3(RuTPU)RU\TPU\pers\34907 |
|
| 701 | 1 |
_aLitvinova _bL. S. |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий (ИШХБМТ) _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210120 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.2174/1381612825666190329153626 | |
| 942 | _cCF | ||