| 000 | 02859nlm1a2200469 4500 | ||
|---|---|---|---|
| 001 | 663726 | ||
| 005 | 20231030041904.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\34896 | ||
| 090 | _a663726 | ||
| 100 | _a20210302a2019 k y0engy50 ba | ||
| 101 | 0 |
_aeng _deng |
|
| 102 | _aUS | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aThe Mitochondrial Permeability Transition Pore – a Regulator of the Resistance of the Heart to Reperfusion _fN. V. Naryzhnaya, L. N. Maslov, Yu. B. Lishmanov [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 130 tit.] | ||
| 330 | _aThe most important event in the formation of reperfusion injury to the heart has been shown to be the opening of mitochondrial permeability transition pores (mPTP). mPTP opening is followed by activation of apoptosis, necroptosis, and cardiomyocyte death. Experimental studies have shown that inhibition of mPTP opening decreases infarct size and that conditioning actions on the myocardium are mediated via decreases in the sensitivity of mPTP to opening factors. The present article reviews existing data on the structure and regulation of mPTP in conditions of reperfusion injury to the heart. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 |
_tNeuroscience and Behavioral Physiology _d1967- |
||
| 463 |
_tVol. 48, iss. 8 _v[P. 943–953] _d2019 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _amyocardium | |
| 610 | 1 | _areperfusion | |
| 610 | 1 | _aMPT pores | |
| 610 | 1 | _amitochondria | |
| 610 | 1 | _aмиокард | |
| 610 | 1 | _aреперфузия | |
| 610 | 1 | _aмитохондрии | |
| 701 | 1 |
_aNaryzhnaya _bN. V. _gNataliya Vladimirovna |
|
| 701 | 1 |
_aMaslov _bL. N. _gLeonid Nikolaevich |
|
| 701 | 1 |
_aLishmanov _bYu. B. _cspecialist in the field of medical technology _clead engineer aof Tomsk Polytechnic University, doctor of medical sciences _f1951- _gYury Borisovich _2stltpush _3(RuTPU)RU\TPU\pers\34200 |
|
| 701 | 1 |
_aNesterov _bE. A. _cPhysicist, Specialist in the field of nuclear power engineering _cResearcher of Tomsk Polytechnic University _f1976- _gEvgeny Alexandrovich _2stltpush _3(RuTPU)RU\TPU\pers\32657 |
|
| 701 | 1 |
_aJaggi _bA. S. _gAmteshwar Singh |
|
| 701 | 1 |
_aSuleiman _bS. _gSaadeh |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет (ТПУ) _bФизико-технический институт (ФТИ) _bЛаборатория № 31 ядерного реактора (Лаборатория № 31 ЯР) _h6471 _2stltpush _3(RuTPU)RU\TPU\col\20054 |
| 801 | 2 |
_aRU _b63413507 _c20210302 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1007/s11055-019-00823-y | |
| 942 | _cCF | ||