| 000 | 03073nlm1a2200517 4500 | ||
|---|---|---|---|
| 001 | 663827 | ||
| 005 | 20231030041909.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\34997 | ||
| 035 | _aRU\TPU\network\34353 | ||
| 090 | _a663827 | ||
| 100 | _a20210311a2020 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aNL | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aSelective antifungal activity of silver nanoparticles: A comparative study between Candida tropicalis and Saccharomyces boulardii _fJ. D. Guerra, G. Sandova, A. Patron [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 43 tit.] | ||
| 330 | _aIn this study, the antifungal activity of AgNPs was tested against C. tropicalis (pathogen fungi) and S. boulardii (probiotic). The effectiveness of the AgNPs was assessed by comparing their antifungal activity with a triazole antifungal drug fluconazole and amphotericin B. The AgNPs have a polygonal-like shape (average size of 35±15 nm) with 1.2% wt. of metallic silver stabilized with 18.8% wt. of polyvinylpyrrolidone (PVP) in 80% wt. of distilled water. The results revealed that 35 [mu]g/mL of fluconazole inhibits 55-60% of both fungal cell growth. As for amphotericin B, 5 [mu]g/mL is sufficient to inhibit more than 95% of both fungal cells. For AgNPs, 25 [mu]g/mL was needed to inhibit 90% of the C. tropicalis cell growth, but remarkably, 50% of the S. boulardii cell population remains viable, which can potentiate cell reproduction. Our results could initiate the development of AgNPs possessing selective specificity against pathogenic fungal species. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tColloid and Interface Science Communications | ||
| 463 |
_tVol. 37 _v[100280, 6 p.] _d2020 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _asilver nanoparticles | |
| 610 | 1 | _aantifungal | |
| 610 | 1 | _aprobiotic | |
| 610 | 1 | _apathogenic | |
| 610 | 1 | _ayeast | |
| 610 | 1 | _aнаночастицы | |
| 610 | 1 | _aсеребро | |
| 610 | 1 | _aпробиотики | |
| 701 | 1 |
_aGuerra _bJ. D. _gJesus |
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| 701 | 1 |
_aSandova _bG. _gGeorgina |
|
| 701 | 1 |
_aPatron _bA. _gAraceli |
|
| 701 | 1 |
_aAvalos-Borja _bM. |
|
| 701 | 1 |
_aPestryakov _bA. N. _cChemist _cProfessor of Tomsk Polytechnic University, Doctor of Chemical Science _f1963- _gAleksey Nikolaevich _2stltpush _3(RuTPU)RU\TPU\pers\30471 |
|
| 701 | 1 |
_aGaribo _bD. _gDiana |
|
| 701 | 1 |
_aSusarrey-Arce _bA. _gArturo |
|
| 701 | 1 |
_aBogdanchikova _bN. _gNina |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210311 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1016/j.colcom.2020.100280 | |
| 942 | _cCF | ||