| 000 | 04241nlm1a2200445 4500 | ||
|---|---|---|---|
| 001 | 663844 | ||
| 005 | 20231030041909.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\35014 | ||
| 090 | _a663844 | ||
| 100 | _a20210312a2021 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aHighly filled poly(l-lactic acid)/hydroxyapatite composite for 3D printing of personalized bone tissue engineering scaffolds _fG. Dubinenko, A. L. Zinovyev (Zinovjev, Zinoviev), E. N. Bolbasov [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 330 | _aThe designing of new biodegradable polymer composites is one of the most promising areas of modern orthopedics and regenerative surgery. At present, a number of methods have been proposed for designing and processing biodegradable polymer composites via various 3D printing technologies; however, the homogeneity of filler distribution together with mechanical properties of scaffolds made of such composites are far from those required for clinical use. In this study, the method for producing biodegradable composite material based on poly(l-lactic acid) (PLLA) solution in organic solvent and hydroxyapatite (HAp) powder was proposed. The influence of HAp weight fraction and additional annealing on PLLA matrix crystallinity was investigated. It was shown that crystallinity of PLLA decreases from 58.84?±?1.21 to 17.33?±?1.69 as HAp weight fraction increased from 0 to 50?wt%. However, HAp filler promoted PLLA crystallites growth according to the X-ray powder diffraction analysis. The results of nanoindentation showed Young's modulus values of the 3D-printed scaffolds with 50?wt% of HAp at the level of human femur and tibia. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tJournal of Applied Polymer Science | ||
| 463 |
_tVol. 138, iss. 2 _v[49662, 4 p.] _d2021 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _abiodegradable | |
| 610 | 1 | _abiomedical applications | |
| 610 | 1 | _acomposites | |
| 610 | 1 | _aextrusion | |
| 610 | 1 | _athermoplastics | |
| 701 | 1 |
_aDubinenko _bG. _cSpecialist in the field of material science _cEngineer of Tomsk Polytechnic University _f1992- _gGleb _2stltpush _3(RuTPU)RU\TPU\pers\42578 |
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| 701 | 1 |
_aZinovyev (Zinovjev, Zinoviev) _bA. L. _cChemist _cJunior Researcher Tomsk Polytechnic University _f1992- _gAlexey Leonidovich _2stltpush _3(RuTPU)RU\TPU\pers\42081 |
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| 701 | 1 |
_aBolbasov _bE. N. _cphysicist _cAssociate Scientist of Tomsk Polytechnic University, Candidate of Sciences _f1981- _gEvgeny Nikolaevich _2stltpush _3(RuTPU)RU\TPU\pers\30857 |
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| 701 | 1 |
_aKozelskaya _bA. I. _cphysicist _cAssistant of Tomsk Polytechnic University, Candidate of physical and mathematical sciences _f1985- _gAnna Ivanovna _2stltpush _3(RuTPU)RU\TPU\pers\39663 |
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| 701 | 1 |
_aShesterikov _bE. V. _cphysicist _cleading engineer of Tomsk Polytechnic University _f1979- _gEvgeny Viktorovich _2stltpush _3(RuTPU)RU\TPU\pers\35793 |
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| 701 | 1 |
_aNovikov _bV. T. _cchemist _cAssociate Professor of Tomsk Polytechnic University, Candidate of chemical sciences _f1946- _gViktor Timofeevich _2stltpush _3(RuTPU)RU\TPU\pers\31286 |
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| 701 | 1 |
_aTverdokhlebov _bS. I. _cphysicist _cAssociate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science _f1961- _gSergei Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\30855 |
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| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИнженерная школа ядерных технологий _bНаучно-образовательный центр Б. П. Вейнберга _h7866 _2stltpush _3(RuTPU)RU\TPU\col\23561 |
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210312 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1002/app.49662 | |
| 942 | _cCF | ||