| 000 | 03608nlm1a2200421 4500 | ||
|---|---|---|---|
| 001 | 663888 | ||
| 005 | 20231030041911.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\35058 | ||
| 035 | _aRU\TPU\network\14827 | ||
| 090 | _a663888 | ||
| 100 | _a20210316a2020 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aStability of a‐C:H:SiOx coating on polypropylene to chemical sterilization _fA. S. Grenaderov, A. A. Soloviev (Solovyev), V. V. Malashchenko, I. A. Khlusov |
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| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 330 | _aPolypropylene (PP) is traditionally used in the production of medical devices, such as catheters, dialyzers, syringes due to its good chemical and thermal resistance, biocompatibility, and low cost. Sterilization can however damage these devices, when the polymer additive releases into physiological fluids, thereby harming the patient health. This article proposes to deposit biocompatible a?C:H:SiOx coatings onto PP surfaces and studies the coating stability after chemical sterilization. Five different chemical sterilizers, namely, hydrogen peroxide, ethanol, miramistin, formaldehyde, and ethylene oxide are used to compare their effect on the coating stability on the PP substrate. Untreated and sterilized samples are incubated in a liquid synthetic nutrient to obtain extracts that are used for sterility testing and determining the degree of interaction of samples with the nutrient medium. The changes in the coating functional groups and surface morphology are examined by using the Fourier transform infrared spectroscopy and the scanning electron microscopy, respectively. It is shown that the a?C:H:SiOx coating has a protective effect on the PP substrates subjected to chemical sterilization. The experiment results clearly showed that the ethanol sterilization causes the most serious changes in the structure of PP, and also leads to the barrier coating failure. On the other hand, ethylene oxide sterilization has a minimal effect on the structure of both uncoated and coated PP substrates. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tJournal of Applied Polymer Science | ||
| 463 |
_tVol. 137, iss. 48 _v[49570, 10 p.] _d2020 |
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| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _abiomedical applications | |
| 610 | 1 | _acoatings | |
| 610 | 1 | _apolyolefins | |
| 610 | 1 | _aбиомедицинские технологии | |
| 610 | 1 | _aпокрытия | |
| 610 | 1 | _aполиолефины | |
| 701 | 1 |
_aGrenaderov _bA. S. _gAleksandr Sergeevich |
|
| 701 | 1 |
_aSoloviev (Solovyev) _bA. A. _cspecialist in the field of hydrogen energy _cAssociate Professor of Tomsk Polytechnic University, Candidate of technical sciences _f1977- _gAndrey Aleksandrovich _2stltpush _3(RuTPU)RU\TPU\pers\30863 |
|
| 701 | 1 |
_aMalashchenko _bV. V. _gVladimir Vladimirovich |
|
| 701 | 1 |
_aKhlusov _bI. A. _cbiophysicist _cProfessor of Tomsk Polytechnic University, doctor of medical Sciences _f1963- _gIgor Albertovich _2stltpush _3(RuTPU)RU\TPU\pers\34907 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210316 _gRCR |
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| 856 | 4 | _uhttps://doi.org/10.1002/app.49570 | |
| 942 | _cCF | ||