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005 20231030041918.0
035 _a(RuTPU)RU\TPU\network\35278
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090 _a664094
100 _a20210326a2020 k y0engy50 ba
101 0 _aeng
135 _adrgn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aOptically responsive delivery platforms: from the design considerations to biomedical applications
_fI. Koryakina, D. Kuznetsova, D. Zuev [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 259 tit.]
330 _aDrug carriers with intelligent functions are powerful therapeutic and diagnostic platforms in curing various diseases such as malignant neoplasms. These functions include the remote noninvasive activation of drug using physical impacts, e.g. light exposure. Combination of different therapeutic modalities (chemotherapy, photodynamic therapy, and so forth) with light-responsive carriers enables promising synergetic effect in tumour treatment. The main goal of this review article is to provide the state of the art on light-sensitive delivery systems with the identification of future directions and their implementation in tumour treatment. In particular, this article reviews the general information on the physical and chemical fundamental mechanisms of interaction between light and carrier systems (e.g. plasmonic and dielectric nanoparticles), the design of optically responsive drug carriers (plain and composite), and the mechanisms of light-driven controlled release of bioactive compounds in biological environment. The special focus is dedicated to the most recent advances in optically responsive bioinspired drug vehicles.
461 _tNanophotonics
463 _tVol. 9, iss. 1
_v[P. 39-74]
_d2020
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _alight-responsive drug carriers
610 1 _arelease mechanisms
610 1 _aplasmonic nanoparticles
610 1 _aresonant dielectric nanoparticles
610 1 _abiomedical applications
610 1 _atumour treatment
610 1 _aсветочувствительные эмульсии
610 1 _aплазмонные наночастицы
610 1 _aбиомедицинские технологии
610 1 _aопухоли
701 1 _aKoryakina
_bI.
_gIrina
701 1 _aKuznetsova
_bD.
_gDarjya
701 1 _aZuev
_bD.
_gDmitry
701 1 _aMilichko
_bV.
_gValentin
701 1 _aTimin
_bA. S.
_cChemist
_cAssociate Scientist of Tomsk Polytechnic University
_f1989-
_gAleksandr Sergeevich
_2stltpush
_3(RuTPU)RU\TPU\pers\37036
701 1 _aZyuzin
_bM. V.
_gMikhail
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИсследовательская школа химических и биомедицинских технологий
_c(2017- )
_h8120
_2stltpush
_3(RuTPU)RU\TPU\col\23537
801 2 _aRU
_b63413507
_c20210514
_gRCR
856 4 _uhttp://earchive.tpu.ru/handle/11683/65321
856 4 _uhttps://doi.org/10.1515/nanoph-2019-0423
942 _cCF