000 | 03225nlm1a2200505 4500 | ||
---|---|---|---|
001 | 664094 | ||
005 | 20231030041918.0 | ||
035 | _a(RuTPU)RU\TPU\network\35278 | ||
035 | _aRU\TPU\network\33560 | ||
090 | _a664094 | ||
100 | _a20210326a2020 k y0engy50 ba | ||
101 | 0 | _aeng | |
135 | _adrgn ---uucaa | ||
181 | 0 | _ai | |
182 | 0 | _ab | |
200 | 1 |
_aOptically responsive delivery platforms: from the design considerations to biomedical applications _fI. Koryakina, D. Kuznetsova, D. Zuev [et al.] |
|
203 |
_aText _celectronic |
||
300 | _aTitle screen | ||
320 | _a[References: 259 tit.] | ||
330 | _aDrug carriers with intelligent functions are powerful therapeutic and diagnostic platforms in curing various diseases such as malignant neoplasms. These functions include the remote noninvasive activation of drug using physical impacts, e.g. light exposure. Combination of different therapeutic modalities (chemotherapy, photodynamic therapy, and so forth) with light-responsive carriers enables promising synergetic effect in tumour treatment. The main goal of this review article is to provide the state of the art on light-sensitive delivery systems with the identification of future directions and their implementation in tumour treatment. In particular, this article reviews the general information on the physical and chemical fundamental mechanisms of interaction between light and carrier systems (e.g. plasmonic and dielectric nanoparticles), the design of optically responsive drug carriers (plain and composite), and the mechanisms of light-driven controlled release of bioactive compounds in biological environment. The special focus is dedicated to the most recent advances in optically responsive bioinspired drug vehicles. | ||
461 | _tNanophotonics | ||
463 |
_tVol. 9, iss. 1 _v[P. 39-74] _d2020 |
||
610 | 1 | _aэлектронный ресурс | |
610 | 1 | _aтруды учёных ТПУ | |
610 | 1 | _alight-responsive drug carriers | |
610 | 1 | _arelease mechanisms | |
610 | 1 | _aplasmonic nanoparticles | |
610 | 1 | _aresonant dielectric nanoparticles | |
610 | 1 | _abiomedical applications | |
610 | 1 | _atumour treatment | |
610 | 1 | _aсветочувствительные эмульсии | |
610 | 1 | _aплазмонные наночастицы | |
610 | 1 | _aбиомедицинские технологии | |
610 | 1 | _aопухоли | |
701 | 1 |
_aKoryakina _bI. _gIrina |
|
701 | 1 |
_aKuznetsova _bD. _gDarjya |
|
701 | 1 |
_aZuev _bD. _gDmitry |
|
701 | 1 |
_aMilichko _bV. _gValentin |
|
701 | 1 |
_aTimin _bA. S. _cChemist _cAssociate Scientist of Tomsk Polytechnic University _f1989- _gAleksandr Sergeevich _2stltpush _3(RuTPU)RU\TPU\pers\37036 |
|
701 | 1 |
_aZyuzin _bM. V. _gMikhail |
|
712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
801 | 2 |
_aRU _b63413507 _c20210514 _gRCR |
|
856 | 4 | _uhttp://earchive.tpu.ru/handle/11683/65321 | |
856 | 4 | _uhttps://doi.org/10.1515/nanoph-2019-0423 | |
942 | _cCF |