| 000 | 03266nlm1a2200385 4500 | ||
|---|---|---|---|
| 001 | 664210 | ||
| 005 | 20231030041922.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\35394 | ||
| 035 | _aRU\TPU\network\28154 | ||
| 090 | _a664210 | ||
| 100 | _a20210331d2021 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aGB | ||
| 135 | _avrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aEffect of working gas on physicochemical and biological properties of CaP coatings deposited by RFMS _fA. I. Kozelskaya, A. Yu. Fedotkin, I. A. Khlusov [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 32 tit.] | ||
| 330 | _aThin calcium phosphate (CaP) coatings were deposited on titanium substrates by radio frequency magnetron sputtering of hydroxyapatite target in neon (Ne), argon (Ar), krypton (Kr) and xenon (Xe). The influence of the working gas (Ne, Ar, Kr and Xe) on the wettability and biodegradation in the RPMI 1640 synthetic culture medium of the CaP coatings was investigated. This paper is the first comprehensive study of working gas effect on properties of the CaP coatings. There was an increase in the polar component of surface free energy (SFE) and a decrease in the dispersion component of SFE with an increase in the atomic mass of the working gas. All CaP coatings had a pronounced protective effect, reducing double the number of dead cells in culture compared to the Ti control. The most soluble CaP coatings formed in the atmosphere of Xe stimulated the hAMMSCs division, which led to an increase in the total number of cells (208% of the initial culture). Samples with CaP coatings formed in an inert gas atmosphere increased the gene expression (ALPL, BMP6, BMP2) in vitro. The most biocompatible coatings were those formed in the atmosphere of Xe and Ar. | ||
| 461 | _tBiomedical Materials | ||
| 463 |
_tVol. 16, iss. 3 _v[035012, 10 p.] _d2021 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 701 | 1 |
_aKozelskaya _bA. I. _cphysicist _cAssistant of Tomsk Polytechnic University, Candidate of physical and mathematical sciences _f1985- _gAnna Ivanovna _2stltpush _3(RuTPU)RU\TPU\pers\39663 |
|
| 701 | 1 |
_aFedotkin _bA. Yu. _cphysicist _cengineer of Tomsk Polytechnic University _f1994- _gAleksandr Yurjevich _2stltpush _3(RuTPU)RU\TPU\pers\44107 |
|
| 701 | 1 |
_aKhlusov _bI. A. _cbiophysicist _cProfessor of Tomsk Polytechnic University, doctor of medical Sciences _f1963- _gIgor Albertovich _2stltpush _3(RuTPU)RU\TPU\pers\34907 |
|
| 701 | 1 |
_aLitvinova _bL. S. _gLarisa Sergeevna |
|
| 701 | 1 |
_aTverdokhlebov _bS. I. _cphysicist _cAssociate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science _f1961- _gSergei Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\30855 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИнженерная школа ядерных технологий _bНаучно-образовательный центр Б. П. Вейнберга _h7866 _2stltpush _3(RuTPU)RU\TPU\col\23561 |
| 801 | 1 |
_aRU _b63413507 _c20150101 _gRCR |
|
| 801 | 2 |
_aRU _b63413507 _c20210331 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1088/1748-605X/abcae3 | |
| 942 | _cCF | ||