| 000 | 04285nlm1a2200529 4500 | ||
|---|---|---|---|
| 001 | 665142 | ||
| 005 | 20231030041953.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\36341 | ||
| 035 | _aRU\TPU\network\27262 | ||
| 090 | _a665142 | ||
| 100 | _a20210825a2021 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aUS | ||
| 135 | _adrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aStudy of the Influence of Morphology, Chemical and Phase Compositions of Zinc Oxide-Containing Silicon and Titanium Oxide Nanomaterials on Cytotoxic Activity _fR. V. Sazonov, A. G. Pershina, O. Ya. Brikunova [et al.] |
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| 203 |
_aText _celectronic |
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| 300 | _aTitle screen | ||
| 320 | _a[References: 42 tit.] | ||
| 330 | _aThe pulsed plasma-chemical method was used to obtain zinc oxide-contthe morphology and histograms of the particle aining silicon and titanium oxide nanocomposites (ZnOx-SiO2 and ZnOx-TiO2). To realize the method, a TEA-500 pulsed electron accelerator (Tomsk, Russia) was used. Zinc oxide (ZnO) nanopowder was obtained using the electrospark method. The morphology and phase composition of the synthesized nanopowders were determined using transmission electron microscopy (TEM) and X-ray diffraction (XRD) methods. The cytotoxicity of ZnO, ZnOx-SiO2, and ZnOx-TiO2 nanomaterials on HepG2 and 3T3-L1 adhesive cell lines was studied using thiazolyl blue tetrazolium bromide (MTT; Sigma). It was found that the size of the synthesized particles was in the range of 40-150 nm. The phase composition of ZnO, ZnOx-SiO2, and ZnOx-TiO2 nanomaterials was presented by several crystal structures. The dominant crystal lattice was ZnO with a hexagonal lattice for the ZnO sample, Zn (hexagonal lattice) for the ZnOx-SiO2 sample, and anatase for the ZnOx-TiO2 sample. The morphology of the ZnO, ZnOx-SiO2, and ZnOx-TiO2 nanoparticles was diverse. The cytotoxicity of ZnOx-SiO2 composite nanomaterials was much lower than that of the ZnO nanoparticles. The effect of increasing the viability of cells under the influence of low doses of ZnOx-TiO2 composite nanomaterials was revealed. These research results may present useful information for specialists involved in the development and application of functional nanocomposites. | ||
| 333 | _aРежим доступа: по договору с организацией-держателем ресурса | ||
| 461 | _tBioNanoScience | ||
| 463 |
_tVol. 11, iss. 2 _v[P. 539-548] _d2021 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 610 | 1 | _apulsed plasma chemical synthesis | |
| 610 | 1 | _acytotoxicity | |
| 610 | 1 | _ananocomposites | |
| 610 | 1 | _aHepG2 | |
| 610 | 1 | _a3Т3-L1 | |
| 610 | 1 | _aплазмохимический синтез | |
| 610 | 1 | _aцитотоксичность | |
| 610 | 1 | _aнанокомпозиты | |
| 610 | 1 | _aхимический состав | |
| 610 | 1 | _aфазовый состав | |
| 610 | 1 | _aоксиды титана | |
| 701 | 1 |
_aSazonov _bR. V. _cphysicist _csenior researcher of Tomsk Polytechnic University, candidate of physico-mathematical Sciences _f1984- _gRoman Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\32698 |
|
| 701 | 1 |
_aPershina _bA. G. _cbiologist _cAssociate Professor of Tomsk Polytechnic University, Candidate of biological sciences _f1981- _gAleksandra Gennadievna _2stltpush _3(RuTPU)RU\TPU\pers\32466 |
|
| 701 | 1 |
_aBrikunova _bO. Ya. _gOlga Yaroslavovna |
|
| 701 | 1 |
_aKholodnaya _bG. E. _celectrophysicist _cAssociate Scientist of Tomsk Polytechnic University, candidate of technical Sciences _f1986- _gGalina Evgenievna _2stltpush _3(RuTPU)RU\TPU\pers\32699 |
|
| 701 | 1 |
_aPonomarev _bD. V. _cphysicist _cSenior researcher of Tomsk Polytechnic University, Candidate of technical sciences _f1981- _gDenis Vladimirovich _2stltpush _3(RuTPU)RU\TPU\pers\32702 |
|
| 701 | 1 |
_aZhirkov _bI. S. _gIgor Sergeevich |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537 |
| 801 | 2 |
_aRU _b63413507 _c20210825 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1007/s12668-021-00858-x | |
| 942 | _cCF | ||