| 000 | 04094nlm1a2200505 4500 | ||
|---|---|---|---|
| 001 | 665613 | ||
| 005 | 20231030042009.0 | ||
| 035 | _a(RuTPU)RU\TPU\network\36816 | ||
| 035 | _aRU\TPU\network\28154 | ||
| 090 | _a665613 | ||
| 100 | _a20211025d2021 k y0engy50 ba | ||
| 101 | 0 | _aeng | |
| 102 | _aGB | ||
| 135 | _avrcn ---uucaa | ||
| 181 | 0 | _ai | |
| 182 | 0 | _ab | |
| 200 | 1 |
_aSolution blow spinning of PLLA/hydroxyapatite composite scaffolds for bone tissue engineering _fA. V. Popkov, D. E. Kulbakin, V. V. Popkov [et al.] |
|
| 203 |
_aText _celectronic |
||
| 300 | _aTitle screen | ||
| 320 | _a[References: 58 tit.] | ||
| 330 | _aComposite poly-L-lactide acid-based scaffolds with hydroxyapatite (HAp) content up to 75 wt.% were fabricated via solution blow spinning. The influence of HAp concentration on structure, wettability, mechanical properties and chemical and phase composition of the produced materials was examined. It was found that with an increase of HAp content the average fiber diameter was increased, the uniaxial strength and relative elongation were reduced, while the phase composition and surface wettability did not change. The performance of the scaffolds during implantation in the parietal bone of a rat skull for a period from 15 to 90 days was studied. The materials have shown high ability to integrate with both soft and hard tissues. It was found that scaffolds with 25 wt.% HAp content significantly enhance osteogenesis during scarification (damage) of the periosteum. Overall, the fabricated scaffolds proved to be highly efficient for replacing bone defects in long tubular bones. | ||
| 461 | _tBiomedical Materials | ||
| 463 |
_tVol. 16, iss. 5 _v[055005, 18 p.] _d2021 |
||
| 610 | 1 | _aэлектронный ресурс | |
| 610 | 1 | _aтруды учёных ТПУ | |
| 701 | 1 |
_aPopkov _bA. V. _gAleksandr Viktorovich |
|
| 701 | 1 |
_aKulbakin _bD. E. _gDenis Evgenjevich |
|
| 701 | 1 |
_aPopkov _bV. V. _gVyacheslav Vladimirovich |
|
| 701 | 1 |
_aGorbach _bE. N. _gElena Nikolaevna |
|
| 701 | 1 |
_aKononovich _bN. A. _gNataljya Andreevna |
|
| 701 | 1 |
_aDanilenko _bN. V. _cchemical engineer _cResearch Engineer, Tomsk Polytechnic University _f1992- _gNadezhda Viktorovna _2stltpush _3(RuTPU)RU\TPU\pers\37547 |
|
| 701 | 1 |
_aStankevich _bK. S. _cPhysicist _cEngineer Tomsk Polytechnic University _f1992- _gKsenia Sergeevna _2stltpush _3(RuTPU)RU\TPU\pers\37546 |
|
| 701 | 1 |
_aChoynzonov _bE. L. _cphysicist _cchief expert of Tomsk Polytechnic University _f1952- _gEvgeny Lkhamatsyrenovich _2stltpush _3(RuTPU)RU\TPU\pers\34575 |
|
| 701 | 1 |
_aZheravin _bA. A. _gAleksandr Aleksandrovich |
|
| 701 | 1 |
_aKhlusov _bI. A. _cbiophysicist _cProfessor of Tomsk Polytechnic University, doctor of medical Sciences _f1963- _gIgor Albertovich _2stltpush _3(RuTPU)RU\TPU\pers\34907 |
|
| 701 | 1 |
_aBondar _bL. N. _gLudmila Nikolaevna |
|
| 701 | 1 |
_aPerelmuter _bV. M. _gVladimir Mikhaylovich |
|
| 701 | 1 |
_aBolbasov _bE. N. _cphysicist _cAssociate Scientist of Tomsk Polytechnic University, Candidate of Sciences _f1981- _gEvgeny Nikolaevich _2stltpush _3(RuTPU)RU\TPU\pers\30857 |
|
| 701 | 1 |
_aTverdokhlebov _bS. I. _cphysicist _cAssociate Professor of Tomsk Polytechnic University, Candidate of physical and mathematical science _f1961- _gSergei Ivanovich _2stltpush _3(RuTPU)RU\TPU\pers\30855 |
|
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИнженерная школа ядерных технологий _bЛаборатория плазменных гибридных систем _h7887 _2stltpush _3(RuTPU)RU\TPU\col\23381 |
| 712 | 0 | 2 |
_aНациональный исследовательский Томский политехнический университет _bИнженерная школа ядерных технологий _bНаучно-образовательный центр Б. П. Вейнберга _h7866 _2stltpush _3(RuTPU)RU\TPU\col\23561 |
| 801 | 1 |
_aRU _b63413507 _c20150101 _gRCR |
|
| 801 | 2 |
_aRU _b63413507 _c20211025 _gRCR |
|
| 856 | 4 | _uhttps://doi.org/10.1088/1748-605X/ac11ca | |
| 942 | _cCF | ||