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100 _a20220125a2021 k y0engy50 ba
101 0 _aeng
102 _aUS
135 _adrgn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aEvaluation of the Bioactive Properties of the Mineral-Polymer Composite Calcium Phosphates – Polylactide
_fT. S. Petrovskaya, N. E. Toropkov, A. N. Fomenko
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 14 tit.]
330 _aThe bioresorption and bioactivity of hybrid composite materials containing calcium phosphates up to 60 wt.% and polylactide (PLA) were studied in situ and in vitro. The resorption dynamics of composites in the PBS model environment was determined. It was found that at calcium phosphate content equal to 40% or more apatite-type calcium phosphates are produced on the surface of composites during incubation in SBF. Composites in the studied range of compositions have a weak cytotoxic effect on the cell culture of Neuro-2a mouse neuroblastoma. The data obtained suggest dynamic resorption and bioactivity of composites in vivo.
333 _aРежим доступа: по договору с организацией-держателем ресурса
338 _bРоссийский фонд фундаментальных исследований
_d19-33-90188
461 _tGlass and Ceramics
463 _tVol. 78, iss. 7-8
_v[P. 317-322]
_d2021
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _acalcium phosphates
610 1 _apolylactide
610 1 _ahydroxyapatite
610 1 _abioactivity
610 1 _aSBF
610 1 _aPBS
610 1 _aгидроксиапатиты
610 1 _aфосфаты кальция
610 1 _aполилактиды
610 1 _aимплантаты
610 1 _aкомпозиционные материалы
610 1 _aбиоактивные композиты
700 1 _aPetrovskaya
_bT. S.
_cChemical Engineer
_cprofessor of Tomsk polytechnic university, doctor of technical sciences
_f1954-
_gTatyana Semyonovna
_2stltpush
_3(RuTPU)RU\TPU\pers\30058
701 1 _aToropkov
_bN. E.
_cChemical engineer
_cEngineer of Tomsk Polytechnic University
_f1992-
_gNikita Evgenievich
_2stltpush
_3(RuTPU)RU\TPU\pers\45800
701 1 _aFomenko
_bA. N.
_cspecialist in the field of medical technology
_cengineer at Tomsk Polytechnic University
_f1985-
_gAlla Nikolaevna
_2stltpush
_3(RuTPU)RU\TPU\pers\35011
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИнженерная школа новых производственных технологий
_bНаучно-образовательный центр Н. М. Кижнера
_h7872
_2stltpush
_3(RuTPU)RU\TPU\col\23556
801 2 _aRU
_b63413507
_c20220125
_gRCR
856 4 _uhttps://doi.org/10.1007/s10717-021-00402-z
942 _cCF