000 02795nlm1a2200481 4500
001 667271
005 20231030042105.0
035 _a(RuTPU)RU\TPU\network\38476
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090 _a667271
100 _a20220311a2017 k y0engy50 ba
101 0 _aeng
102 _aUS
135 _adrcn ---uucaa
181 0 _ai
182 0 _ab
200 1 _aMagnetic resonance imaging and spectroscopy for differential assessment of liver abnormalities induced by Opisthorchis felineus in an animal model
_fA. G. Pershina, V. V. Ivanov, L. V. Efimova [et al.]
203 _aText
_celectronic
300 _aTitle screen
320 _a[References: 95 tit.]
330 _aBackground European liver fluke Opisthorchis felineus, causing opisthorchiasis disease, is widespread in Russia, Ukraine, Kazakhstan and sporadically detected in the EU countries. O. felineus infection leads to hepatobiliary pathological changes, cholangitis, fibrosis and, in severe cases, malignant transformation of bile ducts. Due to absence of specific symptoms, the infection is frequently neglected for a long period. The association of opisthorchiasis with almost incurable bile duct cancer and rising international migration of people that increases the risk of the parasitic etiology of liver fibrosis in non-endemic regions determine high demand for development of approaches to opisthorchiasis detection.
461 _tPLOS Neglected Tropical Diseases
463 _tVol. 11, iss. 7
_v[e0005778, 20 p.]
_d2017
610 1 _aэлектронный ресурс
610 1 _aтруды учёных ТПУ
610 1 _aмагнитно-резонансная томография
610 1 _aспектроскопия
610 1 _aзаболевания
610 1 _aжелчные протоки
610 1 _aинфекции
610 1 _aпечень
701 1 _aPershina
_bA. G.
_cbiologist
_cAssociate Professor of Tomsk Polytechnic University, Candidate of biological sciences
_f1981-
_gAleksandra Gennadievna
_2stltpush
_3(RuTPU)RU\TPU\pers\32466
701 1 _aIvanov
_bV. V.
701 1 _aEfimova
_bL. V.
_gLina Viktorovna
701 1 _aShevelev
_bO. B.
_gOleg
701 1 _aVtorushin
_bS. V.
_gSergey
701 1 _aPerevozchikova
_bT. V.
_gTatjana
701 1 _aSazonov
_bA. E.
_gAlexey
701 1 _aOgorodova
_bL. M.
_gLyudmila Mikhaylovna
712 0 2 _aНациональный исследовательский Томский политехнический университет
_bИсследовательская школа химических и биомедицинских технологий
_c(2017- )
_h8120
_2stltpush
_3(RuTPU)RU\TPU\col\23537
801 2 _aRU
_b63413507
_c20220311
_gRCR
856 4 _uhttps://doi.org/10.1371/journal.pntd.0005778
942 _cCF