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101	0		_aeng
135			_adrcn ---uucaa
181		0	_ai
182		0	_ab
200	1		_aMetal-Free Synthesis of Heteroaryl Amines or Their Hydrochlorides via an External-Base-Free and Solvent-Free C–N Coupling Protocol _fGuang-Gao Fan, Bo-Wen Jiang, Wei Sang [et al.]
203			_aText _celectronic
300			_aTitle screen
320			_a[References: 17 tit.]
330			_aHerein, a metal-free and solvent-free protocol was developed for the C−N coupling of heteroaryl halides and amines, which afforded numerous heteroaryl amines or their hydrochlorides without any external base. Further investigations elucidated that the basicity of amines and specific interactions derived from the X-ray crystallography analysis of 3j′·HCl played pivotal roles in the reactions. Moreover, this protocol was scalable to gram scales and applicable to drug molecules, which demonstrated its practical value for further applications.
333			_aРежим доступа: по договору с организацией-держателем ресурса
461			_tThe Journal of Organic Chemistry
463			_tVol. 86, iss. 21 _v[P. 14627–14639] _d2021
610	1		_aэлектронный ресурс
610	1		_aтруды учёных ТПУ
701		0	_aGuang-Gao Fan
701		0	_aBo-Wen Jiang
701		0	_aWei Sang
701		0	_aHua Cheng
701		0	_aRui Zhang
701		0	_aBao-Yi Yu
701		0	_aYe Yuan
701		0	_aCheng Chen
701		1	_aVerpoort _bF. V. K. _cChemical Engineer _cProfessor of Tomsk Polytechnic University, doctor of chemical Sciences _f1963- _gFrensis Valter Kornelius _2stltpush _3(RuTPU)RU\TPU\pers\35059
712	0	2	_aНациональный исследовательский Томский политехнический университет _bИсследовательская школа химических и биомедицинских технологий _c(2017- ) _h8120 _2stltpush _3(RuTPU)RU\TPU\col\23537
801		2	_aRU _b63413507 _c20220513 _gRCR
856	4		_uhttps://doi.org/10.1021/acs.joc.1c01467
942			_cCF